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Scientists Map the Genetic Regulatory Elements of the Brain

NIH-funded research details the brain’s cellular and molecular regulatory elements and their impact on brain function.News Published: May 24, 2024 | Original story from the National Institutes of Health A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental...

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Pig-organ transplants: what three human recipients have taught scientists

As researchers mark the loss of the first living recipient of a pig kidney, they share what they’ve learnt about xenotransplantation.By Max Kozlov Surgeons transplant a pig kidney into 62-year-old Richard Slayman, who died this month of causes unrelated to the procedure.Credit: Massachusetts General Hospital Last week, the first living person to receive a kidney...

Scientists reveal how our cells’ leaky batteries are making us sick
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Scientists reveal how our cells’ leaky batteries are making us sick

Peer-Reviewed Publication UNIVERSITY OF VIRGINIA HEALTH SYSTEM “NOW THAT WE ARE BEGINNING TO UNDERSTAND HOW THIS INFLAMMATION STARTS, WE MIGHT BE ABLE TO PREVENT THIS PROCESS, WITH THE ULTIMATE GOAL OF LIMITING INFLAMMATION AND TREATING DISEASE,” SAID RESEARCHER LAURA E. NEWMAN, PHD.CREDIT: COURTESY NEWMAN LAB Researchers have discovered how “leaky” mitochondria – the powerhouses of...

More than just neurons: Scientists create new model for studying human brain inflammation
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More than just neurons: Scientists create new model for studying human brain inflammation

by Salk Institute Human astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain. The other half—roughly 85 billion cells—are non-neuronal cells called glia. The most common...

Scientists map the antigenic landscape
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Scientists map the antigenic landscape

by Technical University of Denmark Combined specificity tree for HLA-DR, HLA-DP, and HLA-DQ. Orange molecules have peptide coverage corresponding to at least 50 high-confidence ligands, and blue molecules have a pseudo-sequence distance of at most 0.05 to an orange molecule. Logos in red frames correspond to noncovered molecules. Credit: Jonas Birkelund Nilsson A new paper in...

Scientists on the brink of cure for heart disease – with drugs that ALTER your DNA
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Scientists on the brink of cure for heart disease – with drugs that ALTER your DNA

Are we on the brink of a cure for heart disease? That was the question being whispered by normally cautious cardiologists at the American Heart Association annual conference in Philadelphia last week. Over three packed days, a raft of game-changing scientific discoveries have been unveiled by the world’s leading specialists – many of which will...

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Scientists discover a previously unknown way cells break down proteins

HARVARD MEDICAL SCHOOL At a glance: Scientists have discovered a previously unknown mechanism by which cells break down proteins that are no longer needed.These proteins are short-lived and modulate genes that support important neural, immune, and developmental processes.The mechanism could inform the design of therapies to treat conditions that arise when cells make too much...

Israeli scientists make model to test for breast cancer genetic risk – study
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Israeli scientists make model to test for breast cancer genetic risk – study

According to researchers at Tel Aviv University (TAU), this new model could help with personalized early detection for breast cancer. By JUDY SIEGEL-ITZKOVICH Published: AUGUST 16, 2023 16:47Updated: AUGUST 16, 2023 16:48 A 3D rendering of cancer cells (Illustrative).(photo credit: INGIMAGE)Advertisement Every case of breast cancer in women (and a minority of men) is somewhat different. A new model developed in...

Scientists Discover a New, Unexpected Way That Cancer Cells Spread
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Scientists Discover a New, Unexpected Way That Cancer Cells Spread

HEALTH31 July 2023 By DAVID NIELD Killer T cells surround a cancer cell. (NIH Image Gallery/Flickr/Public Domain) One of the challenges in treating cancer is stopping it from metastasizing, and a new study reveals one of the fundamental mechanisms through which this happens. Now we know about this mechanism, perhaps we can stop it. Key to this newly...

Scientists Discover a New Potential Way To Stop Dementia Progression
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Scientists Discover a New Potential Way To Stop Dementia Progression

By UNIVERSITY OF HELSINKI JUNE 26, 2023 Dementia, a prevalent and distressing neurodegenerative disorder, exerts its grip on countless individuals across the globe. This condition manifests through a progressive decline in cognitive functions, including memory impairment and the inability to carry out routine activities. As the disease advances, individuals grappling with dementia encounter substantial challenges in communication,...

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