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Protein signature identifies those at highest risk from severe infection
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Protein signature identifies those at highest risk from severe infection

by The Francis Crick Institute Graphical abstract. Credit: Immunity (2022). DOI: 10.1016/j.immuni.2022.11.007 Scientists at the Francis Crick Institute have uncovered how a build-up of DNA molecules can impact survival chances in people with severe COVID-19 or sepsis, and have developed a tool that could be used to identify the patients at most risk. Chromatin is a complex...

When severe infection causes long-term mood disorders: Researchers identify promising treatment path
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When severe infection causes long-term mood disorders: Researchers identify promising treatment path

by Pasteur Institute Section of a mouse brain observed using a fluorescence microscope. Credit: Institut Pasteur/Mariana Alonso and Pierre-Marie Lledo The brain is able to detect and regulate localized or systemic inflammation by using two communication pathways. The first, humoral, makes use of specific brain structures that enable circulating inflammatory mediators to enter the brain....