by TranSpread Credit: Burns & Trauma (2024). DOI: 10.1093/burnst/tkae001The increasing prevalence of diabetes worldwide has led to a rise in diabetic wounds, such as diabetic foot ulcers, which are challenging to treat and can result in amputation. Traditional treatments have limited effectiveness, underscoring the urgent need for innovative solutions. In a new study published in...
by International Society for Stem Cell Research A potentially alternative treatment for OA, a debilitating joint disease that affects more than 500 million people worldwide, is the regeneration of cartilage from stem cells. Learn more in Stem Cell Reports about the new work from Zhonghan Li and colleagues that focused on so-called limb bud progenitor...
by University of California, Los Angeles 3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHA UCLA-led team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, offering a deeper understanding of how heart muscle cells develop from their immature fetal stage to their mature...
by Mass General Brigham Credit: Pixabay/CC0 Public Domain Alzheimer’s disease (AD) varies widely in its age of onset, presentation and severity. Recently, the SORL1 gene has received increased attention since variations in this gene have been associated with both early and late onset AD. However, little is known about how damage to SORL1 leads to disease....
MONASH UNIVERSITY CREDIT: JIA TAN, POLO LABORATORY In a groundbreaking study published today in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of Medical Research and The University of Western Australia and Professor Jose M Polo from Monash University and the University of...
by Zen Logsdon, City of Hope National Medical Center City of Hope’s Yanhong Shi, Ph.D., and her colleagues engineered healthy human skin cells containing the functional aspartoacylase (ASPA) gene into induced pluripotent stem cells (iPSCs) and then differentiated the iPSCs into oligodendroglial progenitor cells, the precursor cells that produce myelin, an insulating sheath that wraps around...
Peer-Reviewed Publication INTERNATIONAL SOCIETY FOR STEM CELL RESEARCH Following encouraging results from pre-clinical research and a recent clinical trial on stem cell-based treatments for patients with Type 1 diabetes, researchers are now working on maximizing the function and potential of stem cell-based treatments for future application in patients. More than 8 billion people worldwide live...
by Catherine Diamond, Xi’an jiaotong-Liverpool University DNA being delivered into the nucleus of a stem cell – An artistic rendition of the study led by Dr Gang Ruan and selected as a supplementary cover art by the journal Nano Letters. Credit: American Chemical Society A recent study published in Nano Letters has introduced a new method for delivering particles...
by The Mount Sinai Hospital Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could...
by Cedars-Sinai Medical Center Credit: CC0 Public Domain Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis, a fatal...
