October 4, 2024 by Laurie Kaiser, University at Buffalo Over the last decade, a number of U.S. clinics have marketed stem cell products directly to consumers as purported treatments for a host of diseases and injuries. The problem is that many of these interventions have scant proof of efficacy or safety, noted Laertis Ikonomou, Ph.D.,...
Tag: <span>Stem Cell</span>
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All stem cell therapies are not created equally: Some don’t have many stem cells at all, researchers find
JULY 12, 2024 by University of California – San Diego Credit: Pixabay/CC0 Public Domain Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current “one-cell-cures-all” paradigm in orthopedic stem...
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Stem cell ‘messages’ fast-track healing of diabetic wounds
by TranSpread Credit: Burns & Trauma (2024). DOI: 10.1093/burnst/tkae001The increasing prevalence of diabetes worldwide has led to a rise in diabetic wounds, such as diabetic foot ulcers, which are challenging to treat and can result in amputation. Traditional treatments have limited effectiveness, underscoring the urgent need for innovative solutions. In a new study published in...
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New type of stem cell contains potential for knee cartilage regeneration in arthritic mice
by International Society for Stem Cell Research A potentially alternative treatment for OA, a debilitating joint disease that affects more than 500 million people worldwide, is the regeneration of cartilage from stem cells. Learn more in Stem Cell Reports about the new work from Zhonghan Li and colleagues that focused on so-called limb bud progenitor...
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Scientists find a stem-cell derived mechanism that could lead to regenerative therapies for heart damage
by University of California, Los Angeles 3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHA UCLA-led team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, offering a deeper understanding of how heart muscle cells develop from their immature fetal stage to their mature...
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Stem cell research sheds light on new ‘molecular road’ to Alzheimer’s disease
by Mass General Brigham Credit: Pixabay/CC0 Public Domain Alzheimer’s disease (AD) varies widely in its age of onset, presentation and severity. Recently, the SORL1 gene has received increased attention since variations in this gene have been associated with both early and late onset AD. However, little is known about how damage to SORL1 leads to disease....
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Scientists find way to wipe a cell’s memory to better reprogram it as a stem cell
MONASH UNIVERSITY CREDIT: JIA TAN, POLO LABORATORY In a groundbreaking study published today in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of Medical Research and The University of Western Australia and Professor Jose M Polo from Monash University and the University of...
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Scientists develop universal donor stem cell therapy to treat degenerative brain diseases in a preclinical study
by Zen Logsdon, City of Hope National Medical Center City of Hope’s Yanhong Shi, Ph.D., and her colleagues engineered healthy human skin cells containing the functional aspartoacylase (ASPA) gene into induced pluripotent stem cells (iPSCs) and then differentiated the iPSCs into oligodendroglial progenitor cells, the precursor cells that produce myelin, an insulating sheath that wraps around...
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Improving potential stem cell-based treatments for patients with Type 1 Diabetes
Peer-Reviewed Publication INTERNATIONAL SOCIETY FOR STEM CELL RESEARCH Following encouraging results from pre-clinical research and a recent clinical trial on stem cell-based treatments for patients with Type 1 diabetes, researchers are now working on maximizing the function and potential of stem cell-based treatments for future application in patients. More than 8 billion people worldwide live...
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Researchers overcome stem cell delivery barrier, paving the way for regenerative medicine
by Catherine Diamond, Xi’an jiaotong-Liverpool University DNA being delivered into the nucleus of a stem cell – An artistic rendition of the study led by Dr Gang Ruan and selected as a supplementary cover art by the journal Nano Letters. Credit: American Chemical Society A recent study published in Nano Letters has introduced a new method for delivering particles...