by University of Copenhagen A sensational new study conducted at the University of Copenhagen disproves traditional knowledge of stem cell development. The study reveals that the destiny of intestinal cells is not predetermined, but instead determined by the cells’ surroundings. The new knowledge may make it easier to manipulate stem cells for stem cell therapy. The results have been published in Nature. All cells in the foetal gut have...
Tag: <span>Stemcells</span>
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Family tree of blood production reveals hundreds of thousands of stem cells
Adult humans have many more blood-creating stem cells in their bone marrow than previously thought, ranging between 50,000 and 200,000 stem cells. Researchers from the Wellcome Sanger Institute and Wellcome—MRC Cambridge Stem Cell Institute developed a new approach for studying stem cells, based on methods used in ecology. Credit: CC0 Public Domain The results, published today (5...
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How bone marrow niches keep stem cells thriving
CAR cells are specialized mesenchymal stem cells, which express the specific transcription factors, Ebf1/3, inhibiting osteoblast differentiation to remain undifferentiated, maintain marrow cavities, enhance CXCL12 and SCF expression, and create HSC niches. Hematopoietic stem cells (HSCs) are a class of stem cells located in bone marrow. HSCs give rise to every type of blood cell—from...