Tag: <span>therapeutic cytoreagents</span>

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Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers

Abstract Therapies based on immune cells have been applied for diseases ranging from cancer to diabetes. However, the viral and electroporation methods used to create cytoreagents are complex and expensive. Consequently, we develop targeted mRNA nanocarriers that are simply mixed with cells to reprogram them via transient expression. Here, we describe three examples to establish...