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Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
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Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers

by Van Andel Research Institute Graphical Abstract. Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.04.017 Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers. The new findings, published today in Molecular Cell, reveal for the first time the molecular circuitry by which mutations in the gene STK11 cause inflammation to...