by Hans-Knöll-Institut Resident T cells (purple) survive radiation and chemotherapy in some patients. Donor cells (pink and green) are thus primarily found in the bloodstream. Credit: Daniela Leitner When pathogens enter the human body, a large number of immune cells are quickly on hand to recognize and destroy the invaders. Among them are T cells,...
by National Research Council of Science & Technology Illustration of the proposed pressure-modulated shockwave histotripsy pulsing protocol to control the extent and lifetime of a boiling bubble without inducing the shock scattering effect.P1,+ and P1,- are the peak positive and negative pressures in shockwaves at the HIFU focus. P2,+, and P2,- are those in the...
CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN The body’s circadian clocks enable organs and organ systems to function according to finely tuned daily rhythms. In humans and other mammals, these circadian rhythms are controlled by an area of the brain known as the hypothalamus. Researchers from Charité – Universitätsmedizin Berlin have deciphered an additional, previously unknown mechanism that...
UNIVERSITÉ LIBRE DE BRUXELLES Autoimmune diseases are diseases of “mistaken identity”, where the immune system – which is supposed to protect us against infectious diseases and neoplasias – mistakenly attacks and destroys components of our own body. The incidence of autoimmune diseases is increasing on a worldwide basis, and these diseases – including type 1...
by University of Pittsburgh Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled the field to flourish. Now, a new discovery led by researchers at the University of Pittsburgh School...
Durham, NC – Infection, inflammation, trauma, disease, contact lenses – all of these and more can lead to corneal scarring, which according to the World Health Organization is a leading cause of blindness worldwide. While corneal transplant remains the gold standard to treat this condition, patient demand far outweighs donor supply. However, in a study...
by Osaka University Most tissues of the body have the extraordinary ability to heal themselves upon injury. But sometimes something goes awry during the complex process of wound healing and the tissue forms too much connective tissue, also called fibrosis, around the injured area, which can result in the organ not functioning properly. Now, researchers...
Researchers use in vivo imaging to watch how cells move and generate forces inside living tissues, study sheds new light on how motor proteins generate forces inside living tissues and how genetic factors alter these forces to result in disease COLUMBIA UNIVERSITY SCHOOL OF ENGINEERING AND APPLIED SCIENCE New York, NY–October 28, 2019–Myosins are motor proteins that...
Understanding how stem cells interact with their surroundings could lead to better lab-grown tissues.Credit: Imperial College London Tissues grown in the lab from stem cells may fail to live up their therapeutic promise because the cells choose their own fate. For the last 20 years, scientists have worked to engineer tissues for use in a...
Can generate multiple types of human soft tissues, including skin, skeletal muscles, blood vessels and heart muscles. Researchers at The University of Texas at Arlington have developed a highly elastic biodegradable hydrogel for bio-printing of materials that mimic natural human soft tissues. Bio-printing uses live cells within the scaffolding of the new tissues and could...
