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Mutation in TLR7 increases risk of severe COVID-19
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Mutation in TLR7 increases risk of severe COVID-19

by University of Bonn Single variant exome-wide association study Manhattan plot (MAF>0.1%). QQ-plot available in the S1 Fig. Black dashed line demarcates the genome-wide significance threshold (p < 5×10-8). Credit: PLOS Genetics (2022). DOI: 10.1371/journal.pgen.1010367 Rare gene mutations can significantly increase the risk of severe COVID-19 disease. An international research team with significant contribution from the University...