Research team from University of Göttingen develops drug approach against bacterial infections UNIVERSITY OF GÖTTINGEN FIRST AUTHOR DR. RABE VON PAPPENHEIM EXAMINES PROTEIN CRYSTALS OF A BACTERIAL ENZYME THAT WAS “POISONED ” WITH AN ANTIVITAMIN. view more CREDIT: LISA-MARIE FUNK Antibiotics are among the most important discoveries of modern medicine and have saved millions of...
Opioid receptors in the inner ear can cause partial or full hearing loss, says Rutgers study Opioid use, particularly in high doses, can cause deafness, according to Rutgers researchers. The study, published in The Journal of Medical Toxicology, reviewed records from the New Jersey Poison Control Center, based at Rutgers New Jersey Medical School, from...
At 11 million cases annually, urinary tract infections (UTIs) are the most common outpatient infections in the U.S., according to the U.S. Department of Health and Human Services. At least half of all women will have a UTI during their lifetimes, and many of the infections — which have increasingly become resistant to a wide...
Researchers in the University of Toronto’s Faculty of Applied Science & Engineering have discovered a dose threshold that greatly increases the delivery of cancer-fighting drugs into a tumour. The findings, published recently in the journal Nature Materials, provide a potentially universal method for gauging nanoparticle dosage and could help advance a new generation of cancer...
People low on selenium are at risk of paracetamol overdose, even when they follow dosage recommendations, according to research involving the University of Bath in the UK. UNIVERSITY OF BATH A lack of the mineral selenium in the diet puts people at risk of paracetamol overdose, even when the painkiller is taken at levels claimed...
UNIVERSITY OF WISCONSIN-MADISON MADISON, Wis. — University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans. The technology relies on inserting into...
By Emily Henderson, B.Sc. What led you to carry out this research? When I (James) started graduate school, I had never worked in bacteria before. I originally worked with Drosophila, but when I joined Zemer’s lab, we basically came to the table with the question, “How can we address the global need for new antibiotics...
by NYU Langone Health After a brain injury, cells that normally nourish nerves may actually kill them instead, a new study in rodents finds. This “reactive” phenomenon may be the driving factor behind neurodegenerative diseases like glaucoma, a leading cause of blindness. Led by researchers at NYU Grossman School of Medicine, the study examined what...
by The Scripps Research Institute Scientists at Scripps Research have developed molecules that can remodel the bacterial population of intestines to a healthier state and they have shown—through experiments in mice—that this reduces cholesterol levels and strongly inhibits the thickened-artery condition known as atherosclerosis. The scientists, who report their findings in Nature Biotechnology, created a...
by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, published in Cell Reports Medicine, aims to create a functional HIV cure by activating and then eliminating all pockets of...
