by Michael Haederle, University of New Mexico TFRC is increased in human CRC and is positively correlated with the CTNNB1 protein expression. Detection of TFRC expression in human normal (n = 5–8) and tumor (n = 8) colon tissues by A) qPCR analysis, B) immunoblotting analysis and (C) quantification, and D) immunofluorescence staining and E)...
Tag: <span>tumor development</span>
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Coating cancer cells with silica to create a vaccine that energizes an immune repose to tumor development
by Bob Yirka, Medical Xpress Credit: Pixabay/CC0 Public Domain A team of researchers working at the University of New Mexico Health Science Center has found some success in creating a cancer vaccine by coating cancer cells in silica and injecting them into test mice. In their paper published in the journal Nature Biomedical Engineering, the group...
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New insights on how immune cells are recruited and reprogrammed to drive tumor development
by Karolinska Institutet Low levels of TAp73 correlate with an inflammatory signature and increased activity of the NF-κB pathway in breast cancer. (A) A flowchart of TCGA breast cancer data set analysis. (B) A heatmap based on differential gene set analysis comparing TAp73 low versus TAp73 high expressing samples (FC[Log2]>1, FDR > 0.05). (C) A volcano...