Scientists of Far Eastern Federal University (FEFU), together with German and Russian colleagues, have developed a lead compound to fight chemotherapy-resistant prostate cancer. The original design comes out as scientists combine biologically active molecules from the chemically modified pigment of sea urchins with glucose molecules to deliver the active drug substance inward the tumor cells....
GERMAN CANCER RESEARCH CENTER (DEUTSCHES KREBSFORSCHUNGSZENTRUM, DKFZ) Chimeric antigen receptor (CAR) T cell therapy is a new and in some cases highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system. This promising treatment comes at a cost, however: The manufacturers charge up to EUR 320,000 for the...
by Rockefeller University Press A phase I/II clinical trial by researchers at Stanford University suggests that vaccines prepared from a patient’s own tumor cells may prevent the incurable blood cancer mantle cell lymphoma (MCL) from returning after treatment. The study, which will be published June 19 in the Journal of Experimental Medicine (JEM), reveals that...
by Karolinska Institutet Children who have received radiotherapy for a brain tumor can develop cognitive problems later in life. In their studies on mice, researchers at Karolinska Institutet have now shown that the drug lithium can help to reverse the damage caused long after it has occurred. The study is published in the journal Molecular...
by Shinshu University Grape stems are discarded en masse during the production of wine. We love and produce a lot of wine in Nagano prefecture, and have been hoping to find a positive use for the previously discarded grape stems. Scientists at Shinshu University studied compounds within grape stem extracts and found significant anti-cancer activity...
This news or article is intended for readers with certain scientific or professional knowledge in the field. Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in the cell. The new discovery may in the long term help in the development...
This news or article is intended for readers with certain scientific or professional knowledge in the field. Findings in Mice Point to New Approach That May Help Make Some Metastatic Breast Cancers Susceptible to Immunotherapy. In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found...
Jonathan L. Linehan & Lélia Delamarre Immune cells called CD8 (or cytotoxic) T cells can target and kill cancer cells, and immunotherapies that boost this process are in clinical use. However, for reasons that are not fully clear, it is hard to predict whether a person will respond to this treatment. Writing in Nature, Alspach...
A new drug delivery method designed by researchers at PNNL and Washington State University (WSU) has shown it can target and kill lung cancer cells. The research, led by Chun-Long Chen, a senior research scientist at PNNL and a joint faculty fellow at the University of Washington, and research partner Yuehe Lin, a professor at...
by American Society for Radiation Oncology Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma (HCC), a common but often fatal type of liver cancer for which there are limited treatment options. One study (Sanford et al.) suggests that proton radiation, compared to traditional photon radiation, can extend overall survival with reduced toxicity. A second study (Hsieh et al.) identifies predictors for...
