Tag: <span>uncontrolled inflammation</span>

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Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
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Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers

by Van Andel Research Institute Graphical Abstract. Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.04.017 Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers. The new findings, published today in Molecular Cell, reveal for the first time the molecular circuitry by which mutations in the gene STK11 cause inflammation to...

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New insights into uncontrolled inflammation in COVID-19 patients

QUEEN MARY UNIVERSITY OF LONDON In a new study, published recently in the journal Circulation Research, scientists discover how the production of protective molecules known as specialized pro-resolving mediators (SPM) is altered in patients with COVID-19. The results suggest that treatments that increase SPM production, such as dexamethasone or SPM based drugs, could play a...