News Release 8-Aug-2024 Peer-Reviewed PublicationUniversity of Virginia Health System image: “We hope this discovery will stimulate further work in the treatment of recurrent wheeze and viral infections in children,” said researcher W. Gerald Teague, MD, a pediatric pulmonologist at UVA Health Children’s and the University of Virginia School of Medicine. “The field has to get...
UNIVERSITY OF ROCHESTER MEDICAL CENTER IMAGE: STUDY IN SCIENCE SHOWS HOW A CAS PROTEIN PARTNERS WITH A UNIQUE MEMBRANE PROTEIN TO STOP VIRAL INFECTION IN BACTERIA. CREDIT: UNIVERSITY OF ROCHESTER MEDICAL CENTER CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that...
By Neha Mathur Feb 3 2023 Reviewed by Danielle Ellis, B.Sc. In a recent study published in Microorganisms, researchers briefly outlined how viral infections trigger endocrinopathies in humans. Study: Viruses and Endocrine Diseases. Image Credit: mediatext/Shutterstock Background Viruses can transiently or permanently damage endocrine organs by directly attacking endocrine cells or via indirect mechanisms. It activates the...
by Ohio State University Medical Center Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID A new study by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests a...
by American Association for Cancer Research Credit: Unsplash/CC0 Public Domain Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases, according to a publication in...
by Lindsay Brownell, Harvard University Graphical abstract. Credit: Molecular Therapy – Nucleic Acids (2022). DOI: 10.1016/j.omtn.2022.08.031 RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many types of non-living viruses, however, carry their genetic information in a double-stranded form of RNA (dsRNA). When the...
by Peter Doherty Institute for Infection and Immunity Credit: Nature Immunology (2022). DOI: 10.1038/s41590-022-01273-4. https://www.nature.com/articles/s41590-022-01273-4 Researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) have identified how to increase the ability of tissue-resident memory T (TRM) cells to help fight viral infections and certain cancers. This discovery adds to the growing knowledge around the huge...
by The Peter Doherty Institute for Infection and Immunity Immune cells (T cells, green) can be see entering the cornea of the eye, towards the Herpes Simplex virus infected cells (light blue). The eye is rich in nerves (purple). Credit: Doherty Institute The cornea—the transparent protective outer layer of the eye critical to helping us...
by McMaster University Credit: CC0 Public Domain McMaster University researchers have found not only how some viral infections cause severe tissue damage, but also how to reduce that damage. They have discovered how Type I interferon (IFN) stops the immune system from “going rogue” and attacking the body’s own tissues when fighting viral infections, including COVID-19....
by Delthia Ricks, Medical Xpress Characterisation of memory B cell responses in mice after influenza infection. (A) Representative gating for memory B cells. After doublet, dead and CD3+, F4/80+ and streptavidin-specific cells were removed, CD45+ B220+ IgD- lymphocytes were gated before assessing binding to HA- or NP-probes within memory populations (GL7-CD38hi). (B) Proportion of blood-circulating (IV+; red) and tissue-resident...
