September 13, 2024 by Ernie Mundell An ingredient in the hair dye a French woman used caused her to develop a vision-robbing retinopathy, researchers report. When she switched to a dye without these ingredients, called aromatic amines, her vision troubles resolved, according to a team led by Dr. Nicolas Chirpaz, an ophthalmologist at Edouard Herriot...
August 15, 2024 by Homa Warren, Baylor College of Medicine Credit: CC0 Public DomainA person can begin to lose their eyesight at any age, and recognizing the signs and symptoms of vision loss is important to their eye health. An ophthalmologist at Baylor College of Medicine says noticing these signs is especially significant in young...
by University of Virginia FTO in macrophage VEGFA release and choroidal neovascularization. a Quantification of Vegfa, m6A methyltransferase (Mettl3, Mettl4), demethylase (Fto) mRNA levels in pooled eye tissues (n = 3) of control, naive (no laser treated) mice (Ctrl) or mice following laser injury (choroidal neovascularization, CNV, day 3 after laser injury). b, c Immunofluorescent staining of...
by Dresden University of Technology Microscopic images of lab-grown mini-retinas, so called human retina organoids. The left image shows a section of a healthy (control) organoid, whereas the right image shows an organoid section with pathological changes. On the right, there is a massive loss of photoreceptor neurons that are labeled in green. The red...
by Sanford Burnham Prebys Medical Discovery Institute Vitronectin illustration. Credit: Sanford Burnham Prebys/Francesca Marassi Research led by Sanford Burnham Prebys professor Francesca Marassi, Ph.D., is helping to reveal the molecular secrets of macular degeneration, which causes almost 90% of all age-related vision loss. The study, published recently in the Biophysical Journal, describes the flexible structure of...
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE IMAGE: THE FIGURE SHOWS THAT BLACKS HAD A 2-FOLD INCREASED RISK FOR EARLY LOSS ARCHETYPES COMPARED TO NON-HISPANIC WHITES. BLACKS HAD A 5-FOLD INCREASED RISK OF ADVANCED LOSS ARCHETYPES. THE DIFFERENCE IN INCREASED RISK FOR BLACKS BETWEEN THE ADVANCED LOSS ARCHETYPES VERSUS THE EARLY LOSS...
Inhibiting ceramide accumulation in retina protects photoreceptors, improves vision. Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the retina, leads to an accumulation of ceramides in the retina, resulting in progressive photoreceptor cell death and ultimately...
by University of California, Irvine “AdipoR1 is one of the principal enzymes that regulate ceramide content in the eye,” says first and co-corresponding author Dominik Lewandowski, Ph.D., postdoctoral scholar at the UCI School of Medicine. “Ceramide accumulation is detrimental for the retina and has been associated with non-syndromic retinitis pigmentosa. Our study showed that this...
UNIVERSITY OF CALIFORNIA – DAVIS Regularly eating a small serving of dried goji berries may help prevent or delay the development of age-related macular degeneration, or AMD, in healthy middle-aged people, according to a small, randomized trial conducted at the University of California, Davis. AMD is the leading cause of vision loss in older people, and is estimated...
by University of Melbourne Retinal microglia associate with vasculature and neuronal synapses. (A) Whole-mounted mouse retina (Cx3cr1GFP/+) was labeled with anti-EGFP (microglia, green), and G. simplicifolia IB4 (blood vessels, red). The highlighted region shows microglial association with vessels within the superficial vascular plexus (Inset). (Scale bars, 500 µm; 50 µm, Inset.) (B) The association of...
