12 Medications That Cause Hair Loss

Written by Austin Ulrich, PharmD, BCACP | Reviewed by Joshua Murdock, PharmD, BCBBS

Updated on January 12, 2024print_outlinedemail_outlined

Key takeaways:

• There are many medications that may cause hair loss. These medications can cause hair to thin or come out in clumps. Common examples include chemotherapy, antidepressants, and anti-seizure medications.
• Oral retinoids, tamoxifen, and blood thinners can also cause hair loss. It usually reverses once you stop taking the medication, but in some cases it can be permanent.
• It’s best to talk to your healthcare provider about hair loss caused by medication — don’t try to treat it on your own. They can recommend the best treatment option or make changes to your medications to help reverse or manage hair loss safely.

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Table of contents

Retinoids

Antidepressants

Blood thinners

Anti-seizure meds

Beta-blockers

Antithyroid meds

Chemotherapy

Tamoxifen

Some arthritis meds

Allopurinol

Levodopa

Ozempic

Treating hair loss

Bottom line

References

“Rattankun Thongbun”/iStock via Getty Images

If you or someone you know has experienced hair loss, you know how distressing this condition can be. Even though it’s not a life-threatening problem, it can harm your self-image and quality of life. Sometimes hair loss is caused by the natural aging process, such as hormone changes. It can also be caused by genetics. But many medications can cause hair loss, too.

Chemotherapy is the most well-known type of medication that causes hair loss. But what are the other medications that cause hair loss you should be aware of? And is there anything you can do to prevent it? Let’s take a look at the most common medications that may cause hair loss.

1. Retinoids

Retinoids are a class of medications that are used to treat skin conditions such as acne and discoloration. They’re derived from vitamin A and help lower inflammation and promote cell turnover.

Oral retinoids, like isotretinoin (Absorica), are known to cause telogen effluvium in some people. Telogen effluvium is when hair comes out in clumps. For example, you may notice more hair collecting in your hairbrush or in the shower. 

Hair loss seems to happen more often with higher doses of oral retinoids. But it’s often reversible after you finish the treatment course. You’ll typically take oral retinoids for 15 to 20 weeks. But if hair loss is severe or becomes concerning for you, talk to your healthcare provider. They may have you stop taking the medication sooner.

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2. Antidepressants

Antidepressants are a class of medications that are used to treat mood disorders, such as depression, anxiety, and bipolar disorder. They work by affecting certain chemicals in the brain. 

Several antidepressants may cause hair loss, but the reason why is unclear. Commonly used antidepressants that may cause hair loss include:

• Bupropion (Wellbutrin)
• Selective serotonin reuptake inhibitors (SSRIs), such as fluvoxamine (Luvox)
• Serotonin and norepinephrine reuptake inhibitors (SNRIs), such as duloxetine (Cymbalta), venlafaxine (Effexor), and desvenlafaxine (Pristiq)

According to one study, bupropion may have a higher risk of hair loss compared with other antidepressants.

Hair loss usually reverses once you stop taking an antidepressant. But you shouldn’t stop taking an antidepressant on your own. This can cause serious side effects, especially if you’ve been taking it for a while. Your healthcare provider can help you stop taking an antidepressant safely if it’s causing problematic hair loss. 

3. Anticoagulants

Anticoagulants are a class of medications that are used to prevent blood clots. These medications are also called “blood thinners,” and they work by stopping blood clots from forming. 

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Hair loss is a possible side effect of anticoagulants. It can appear anywhere from weeks to years after starting the medication. Telogen effluvium seems to be the most common type of hair loss seen with anticoagulants. But the exact cause is unknown.

Anticoagulants associated with hair loss include:

• Heparin
• Warfarin (Coumadin, Jantoven)
• Apixaban (Eliquis)
• Rivaroxaban (Xarelto)

If hair loss is an issue, your healthcare provider may try switching you to a different blood thinner. But you shouldn’t make any changes to your anticoagulant medication without their OK. 

4. Anticonvulsants

Anticonvulsants, also known as antiepileptics, are a class of medications that are used to treat and prevent seizures. They work by stabilizing the electrical activity in the brain. Some anticonvulsants are also used to treat certain mood disorders, such as bipolar disorder.

Hair loss has been reported with anticonvulsant medications. One review found hair loss was more common with valproic acid (Depakote) and pregabalin (Lyrica), but less common with levetiracetam (Keppra).

5. Beta blockers

Beta-blockers are a class of medications that treat high blood pressure and other heart conditions. Beta blockers can cause telogen effluvium, but it’s not common. 

Commonly used beta blockers include:

• Propranolol (Inderal)
• Atenolol (Tenormin)
• Metoprolol (Lopressor, Toprol XL)

You may have heard that losartan (Cozaar) — a different type of blood pressure medication — can cause hair loss. But hair loss is not a known side effect of losartan. 

6. Antithyroid medications

Thyroid conditions can cause hair loss on their own. And antithyroid medications used to treat an overactive thyroid (hyperthyroidism) can also contribute to hair loss. Examples of these medications include methimazole (Tapazole) and propylthiouracil. 

Let your provider know if hair loss becomes an issue while you’re taking an antithyroid medication. They may want to check your thyroid hormone levels to make sure they’re where they should be and adjust your medication if needed.

7. Chemotherapy

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Chemotherapy is a common cancer treatment that works by killing cancer cells. But it also kills other fast-growing cells in your body, and that includes your hair cells. This type of hair loss is called anagen effluvium.

Hair loss typically begins days to weeks after receiving chemotherapy. And hair loss effects are often fairly noticeable after 1 to 2 months. Commonly used chemotherapy medications that can cause hair loss include cyclophosphamide (Cytoxan) and doxorubicin (Adriamycin).

Cooling caps, gentle brushing, and avoiding heat-based styling devices may help lessen hair loss. But there’s not a foolproof way to prevent it. The good news is that hair typically grows back 1 to 3 months after completing chemotherapy treatment.

8. Tamoxifen

Tamoxifen is a medication that’s used to treat or prevent breast cancer. It’s known to cause hair loss or hair thinning due to its estrogen-blocking effect. 

Hair will usually regrow when treatment is completed. But you’ll typically take tamoxifen for several years. So talk to your provider about treatment options if hair loss is bothersome while you’re taking tamoxifen.

9. Certain arthritis medications

Certain medications used to treat rheumatoid arthritis and other autoimmune conditions may also cause hair loss. For example, traditional disease-modifying antirheumatic drugs (DMARDs) — such as methotrexate and leflunomide (Arava) — cause hair loss because they can stop or slow down hair growth. 

Although rare, biologic DMARDs — such as etanercept (Enbrel) and adalimumab (Humira) — can also cause hair loss. But it’s not fully understood why this happens.

10. Allopurinol

Allopurinol (Zyloprim) is a medication that’s used to treat gout. It’s been linked to hair loss, but this seems to come from limited case reports. So it’s not clear how likely hair loss is while you’re taking allopurinol. But if it happens, let your provider know. A different gout medication may be a better option for you.

11. Levodopa

Sinemet (carbidopa/levodopa) is a medication used to treat symptoms of Parkinson’s disease. Levodopa — one of the medications in Sinemet — may cause hair loss. Levodopa works like dopamine in the body, and dopamine seems to prevent hair growth in some people. Bromocriptine (Parlodel) is another medication that acts like dopamine in the body and may cause hair loss.

Hair loss from levodopa or bromocriptine isn’t common, but let your provider know if it happens to you. They can help you stop taking Sinemet safely if needed to manage this side effect. But don’t stop taking it on your own. It can be dangerous to abruptly stop taking levodopa.

12. Ozempic and other semaglutide medications

Some people taking semaglutide medications, such as Wegovy or Ozempic, reported hair loss in clinical trials. It’s not clear if this is from the medication itself or if it’s due to the weight loss seen with these medications. That’s because losing weight rapidly is a known cause of hair loss.

In most cases, hair loss should reverse as your body adjusts. But let your provider know if it doesn’t. It’s possible that you’re not getting enough nutrients or there’s another cause of your hair loss.

How to treat hair loss caused by medication

Medication-related hair loss may be permanent, but it can usually be reversed by stopping the medication causing it. Keep in mind that stopping your medication isn’t always an option. And it’s not something you should do on your own.

There may be other treatment options for hair loss caused by medication. Topical treatments such as minoxidil (Rogaine) may help. Certain supplements, such as vitamin C and omega-3 fatty acids, may also help in certain situations. But the right treatment depends on what’s causing hair loss and what type of hair loss it is. And not all hair loss caused by medication can be treated.

Talk to your healthcare provider before trying any hair-loss treatments on your own. They can make sure they won’t interfere with your other medications. And they can help recommend the options that are likely to work best for your specific situation. They may also be able to change the medication that’s causing hair loss to a different treatment option. 

The bottom line

Hair loss is often associated with getting older or chemotherapy. But there are other medications that can cause hair loss too. Some examples include oral retinoids, blood thinners, and antidepressants. Anti-seizure medications, beta blockers, and antithyroid medications are also known to cause hair loss for some people.

In most cases, hair loss caused by medication is temporary. Lost hair will usually regrow once the medication is stopped. But sometimes, stopping medication isn’t an option. And although rare, hair loss triggered by a medication can be permanent.

Let your healthcare provider know if you think your medication is affecting your hair. They may recommend a treatment option to help the hair regrow. Or they may be able to change the medication causing hair loss to a different treatment option.

Why trust our experts?

Written by:

Austin Ulrich, PharmD, BCACP

Austin Ulrich, PharmD, BCACP, is a board-certified ambulatory care clinical pharmacist. In his early career, he provided direct patient care in a variety of settings, including hospital and community pharmacies, and in a primary care clinic as a clinical pharmacist.

Edited by:

Stacia Woodcock, PharmD

Stacia Woodcock, PharmD, is a pharmacy editor for GoodRx. She earned her Doctor of Pharmacy degree from the University of Kentucky and is licensed in New York and Massachusetts.

Reviewed by:

Joshua Murdock, PharmD, BCBBS

Joshua Murdock, PharmD, BCBBS, is a licensed pharmacist in Arizona, Colorado, and Rhode Island. He has worked in the pharmacy industry for more than 10 years and currently serves as a pharmacy editor for GoodRx.

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References

Chen, B., et al. (2015). Cosmetic side effects of antiepileptic drugs in adults with epilepsy. Epilepsy and Behavior. 

Etminan, M., et al. (2018). Risk of hair loss with different antidepressants. International Clinical Psychopharmacology. 

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