University of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumors including triple-negative breast cancer. Two University of Colorado Cancer Center studies were presented this weekend at the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Meeting in Philadelphia, PA showing that using the...
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Magnesium, T2DM link seen in poor-carbohydrate-quality diet
(HealthDay)—The correlation between higher magnesium intake and reduced risk of type 2 diabetes is stronger in the context of poor-carbohydrate-quality diets, according to a study published online Oct. 4 in Diabetes Care. Adela Hruby, Ph.D., M.P.H., from Tufts University in Boston, and colleagues assessed dietary intake from food frequency questionnaires every four years for participants in...
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Topical gel made from oral blood pressure drugs shown effective in healing chronic wounds
IMAGE: WOUND. An international team of researchers led by Johns Hopkins has shown that a topical gel made from a class of common blood pressure pills that block inflammation pathways speeds the healing of chronic skin wounds in mice and pigs. A report of the findings, published Oct. 16 in the Journal of Investigative Dermatology, marks efforts...
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Researchers discover eight new epilepsy genes
Generalized 3 Hz spike and wave discharges in a child with childhood absence epilepsy. Approximately 30 per cent of patients with epilepsy do not respond to anti-epileptic drugs. In these cases, all neurologists can do is attempt to find the right combination of medication through trial and error. A treatment that could target the...
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RefEx, a web tool for a comfortable search of reference data for gene expression analysis
You can search gene expression data by gene name or ID, etc. Tissue-specific genes can be browsed by clicking tissue icons. Currently, there are many public databases available to everyone in the field of life science, but there are many problems when you try to use them, namely you do not know which to...
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Butterfly iQ, a Whole Body Ultrasound That Fits in a Pocket
Butterfly Network, a firm based in Guilford, Connecticut, won FDA clearance and is introducing its Butterfly iQ portable ultrasound system. It consists of a portable transducer that connects directly to an iPhone, and an iOS app to display the images and to control settings. The device actually works as three different transducers thanks to an...
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Scientists ‘completely CURE’ bowel cancer in mice using a form of pioneering immunotherapy and say it could kill ‘virtually ALL’ tumor types
Immunotherapy teaches the body to attack cancer cells and destroy tumors A US team developed a new type of radioimmunotherapy, which combines traditional radiation therapy and immunotherapy Until now, this has had limited success eradicating tumors, say the researchers The new treatment works because it delivers the correct amount of radiation However, a limitation of...
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For the first time, researchers control cells’ chromatin to prevent cancer from adapting to treatment
Northwestern Engineering’s Vadim Backman has developed an effective new strategy for treating cancer, which has wiped out the disease to near completion in cellular cultures in the laboratory. The treatment works by controlling chromatin, a group of macromolecules—including DNA, RNA, and proteins—that houses genetic information within cells and determines which genes get suppressed or expressed. In the case of cancer,...
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How Helicobacter pylori causes gastric cancer
A) Healthy epithelial tissue compared with infected epithelial tissue (green) in the human stomach destroyed by Helicobacter pylori. B) Three magnified bacteria (light green) viewed under an electron microscope. Red arrows indicate the …more Gastric cancer is one of the five most fatal types of cancer. According to the statistics of the World Health Organization...
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GPs should not prescribe antibiotics for sinus infections, health watchdog warns and patients should instead ‘take it easy’ and dose up on paracetamol
New Nice guidance stresses that most sinus infections will resolve on their own Patients should instead ‘take it easy’ and dose up on paracetamol, advice states It was based on statistics which show doctors are wrongly prescribing the drugs It’s estimated the rise of super-bugs will kill 10 million people each year by 2050 GPs...