Patients with neuroendocrine tumours that have spread beyond the intestines should not have surgery before they present with abdominal-related symptoms. This is shown in a new study by researchers at Uppsala University, who hope the results will have major significance, especially for the many patients who may run a reduced risk of unnecessary surgeries and...
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Circulating tumor cells associated with relapse in late-stage melanoma patients
A study revealing a connection between circulating tumor cells (CTCs) and relapse in stage IV melanoma patients points to liquid biopsy as a potential predictor of patients at high risk for disease progression. CTCs, tumor cells shed into the bloodstream or lymphatic system, can lead to additional tumor growth and/or metastasis to distant sites. Findings...
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Cancer cells destroyed in just 3 days with new technique
Cancer cells are relentless, possessing the vexatious ability to develop resistance to current therapies and making the disease hugely challenging to treat. However, an exciting new study may have identified cancer’s weak spot; the discovery has already led to the near-eradication of the disease in cell cultures. Altering the structure of chromatin in cancer cells could...
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Immune cells mistake heart attacks for viral infections
By using single cell RNA Seq, an emerging technique that combines microfluidic nanoliter droplet reactors with single cell barcoding and next generation sequencing, the researchers were able to examine expression of every gene in over 4,000 …more A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has...
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Clinical trial finds blood-plasma infusions for Alzheimer’s safe, promising
In a small safety trial based on preclinical work by a Stanford researcher, participants receiving blood plasma infusions from young donors showed some evidence of improvement. Sharon Sha presented findings Nov. 4 from a small clinical trial that found administering blood plasma from young donors to people with mild to moderate Alzheimer’s disease was safe....
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Want to get rid of cellulite? There’s only one thing worth trying
Contrary to what dozens of “cellulite solutions” companies want you to believe Also, the only way to get a beach body is to put your body on a beach. No one wants to hear that there’s no solution to the problem that vexes them. And while we might be loathe to admit it, we don’t...
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New Therapies Approved for Multiple Myeloma
Abstract and Introduction Abstract Multiple myeloma (MM) accounts for approximately 1% of all cancers and 10% of all hematologic malignant disorders. MM occurs slightly more often in men than in women, and it is twice as common in African American persons compared with white persons. The median age at diagnosis is approximately 65 years. Although...
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Immune cell policing offers insights into cancer, autoimmune disease
Skin samples from mice whose regulatory immune cells (Tregs) lack the Lkb1 protein (bottom) are under attack from other immune cells (purple dots) compared to normal mice whose Tregs have the Lkb1 protein (top). Regulatory T cells (Tregs) are the traffic cops of the immune system. They instruct other types of immune cells on...
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Why your muscles hurt so much the day after you work out
If you do end up with achy muscles after a workout, your best bet is to stretch and keep hydrated. Ever woken up the day after a workout and wondered what you did to deserve such pain? I’m talking about soreness. That pain can stem from several sources, and understanding what’s behind yours will help...
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The battle between cancer and the immune system—who switches the off signals off?
Research centred on PDL1, an ‘immune checkpoint’ protein and prominent target of cancer immunotherapies. Scientists have discovered key new information about how to boost our immune system’s fight against cancer. Their research revealed a trick that healthy cells use to prevent undue suppression of the immune response. The study, by scientists from the University of York,...