Scientists have found it challenging to understand why some breast cancers become resistant to drugs. A recent study concludes that a sticky protein might be the answer. A glue-like protein may help to explain breast cancer drug resistance. The hormone estrogen plays a vital part in the development of breast cancer. An estimated 70 percent of all breast cancers are...
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Study finds mutation driving deadlier brain tumors and potential therapy to stop it
July 9, 2018, Perelman School of Medicine at the University of Pennsylvania A poorly understood mutation in the brain cancer glioblastoma (GBM) is now being implicated for the first time as the driver of rare but deadlier cases of the disease, a team of researchers from the Perelman School of Medicine at the University of Pennsylvania and the...
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Huntington’s disease—how brain training games could help
July 9, 2018 by Emma Yhnell, The Conversation In the search for new treatments, science often focuses on medication first. But drugs aren’t the only way to fight illness, particularly when looking at brain diseases. My research looks into how playing specially designed computer games might help people who are living with Huntington’s disease. Huntington’s is a brain disorder that gets...
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New targets found to reduce blood vessel damage in diabetes
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY AUGUSTA, Ga. (July 9, 2018) – In diabetes, both the tightly woven endothelial cells that line our blood vessels and the powerhouses that drive those cells start to come apart as early steps in the destruction of our vasculature. IMAGE: THIS IS DR. MASUKO USHIO-FUKAI. Now scientists have evidence...
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Candidate AIDS vaccine passes key early test
Paris (AFP) – The near 40-year quest for an AIDS vaccine received a hopeful boost Saturday when scientists announced that a trial drug triggered an immune response in humans and shielded monkeys from infection. Scientists announced that a trial drug against the AIDS vaccine has yielded encouraging results and has advanced to the next phase...
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Scientists identify a protein complex that shapes the destiny of T cells
July 6, 2018, St. Jude Children’s Research Hospital Like a mentor helping medical students choose between specialties, a protein complex helps shape the destiny of developing T cells, St. Jude Children’s Research Hospital scientists have reported. The research appears today in the journal Science Immunology and adds to growing evidence of the critical role cell metabolism plays in the immune system. Corresponding author Hongbo...
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Scientists identify body’s microreactors for innate immunity
July 6, 2018 by Deborah Wormser, UT Southwestern Medical Center A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity—the body’s first response to infection, UT Southwestern researchers report. The work, reported today in the journal Science, could lead to novel treatments for infections, autoimmune disease, and cancer. (l-r) Mingjian Du and Dr....
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Mayo Clinic Researchers Use Targeted Sequencing to Diagnose Short Telomere Syndrome
NEW YORK (GenomeWeb) – A team from the Mayo Clinic has examined the genetic and phenotypic features that occurs in individuals diagnosed with short telomere syndrome (STS), a condition resulting in symptoms that range from accelerated aging or bone marrow failure to immune and multiple organ problems. “With the help of this patient series, we...
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Signs of alcohol withdrawal syndrome
Alcohol withdrawal syndrome is the group of symptoms that can develop when someone with alcohol use disorder suddenly stops drinking. Alcohol use disorder was formerly known as alcohol addiction or alcoholism. If a person regularly drinks too much alcohol, their body may become dependent on the substance. Alcohol is a depressant. Alcohol use disorder or drinking heavily over...
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Healthy diet may lower eye disease risk
An analysis of recent high-quality research reveals that diet may affect individuals’ risks related to the development and progression of age-related macular degeneration (AMD). The findings are published in Clinical & Experimental Ophthalmology. The systematic review included the analysis of 18 high-quality studies. Adherence to a Mediterranean diet was linked with a decreased risk of AMD progression....