by NIH/National Institute on Aging A recently recognized brain disorder that mimics clinical features of Alzheimer’s disease has for the first time been defined with recommended diagnostic criteria and other guidelines for advancing and catalyzing future research. Scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly-named pathway to dementia, Limbic-predominant Age-related...
Post
Study links patrolling monocytes to lupus-related kidney disease
by St. Jude Children’s Research Hospital This work shows for the first time that a type of immune cell called a patrolling monocyte plays a critical role in lupus-related kidney disease. Authors Vanessa Redecke, M.D., Ph.D., Hans Haecker, M.D., Ph.D., and Jeeba Kuriakose, Ph.D. Credit: St. Jude Children’s Research Hospital A study led by St. Jude Children’s Research...
Post
Microscopic worms could provide key to repairing injured nerves
by University of Queensland A tiny worm’s ability to repair damaged nerves could one day help people with nerve injuries such as paralysis, according to University of Queensland research. A team led by Professor Massimo Hilliard, Dr. Rosina Giordano-Santini and Dr. Casey Linton from UQ’s Queensland Brain Institute and Dr. Brent Neumann from Monash University has discovered keyinformation on how...
Post
Deadly box jellyfish antidote discovered using CRISPR genome editing
by University of Sydney Researchers at the University of Sydney have discovered an antidote to the deadly sting delivered by the most venomous creature on earth—the Australian box jellyfish. The Australian box jellyfish (Chironex fleckeri) has about 60 tentacles that can grow up to three metres long. Each tentacle has millions of microscopic hooks filled with venom. Each box jellyfish carries enough venom to kill more than 60 humans. A single...
Post
Army research may be used to treat cancer, heal combat wounds
U.S. ARMY RESEARCH LABORATORY RESEARCH TRIANGLE PARK, N.C. (May 1, 2019) – Army research is the first to develop computational models using a microbiology procedure that may be used to improve novel cancer treatments and treat combat wounds. Using the technique, known as electroporation, an electrical field is applied to cells in order to increase the permeability of the cell membrane, allowing chemicals, drugs, or DNA to be introduced into the cell....
Post
Do microglia hold the key to stop Alzheimer’s disease?
by VIB (the Flanders Institute for Biotechnology) A Leuven research team led by Prof. Bart De Strooper (VIB-KU Leuven, UK DRI) studied how specialized brain cells called microglia respond to the accumulation of toxic proteins in the brain, a feature typical of Alzheimer’s. The three major disease risk factors for Alzheimer’s—age, sex and genetics—all affect microglia response, raising the possibility that drugs that modulate...
Post
Right combination of diet and bacteria limits cancer progression
by University of Luxembourg Diet can have significant effects on the gut microbiome, the populations of microorganisms such as bacteria that live in the human gut. It is well recognised that through complex metabolic interactions, dietary habits contribute to cancer prevention. More specifically, diets rich in fibre reduce the risk of developing specific cancers such as...
Post
Blood based test using AI and nanotechnology devised for chronic fatigue syndrome
By Dr. Ananya Mandal, MD People suffering from chronic fatigue syndrome (CFS) have been up until now treated with scepticism at best. Their symptoms have been negated as vague and their debilitating condition has not received the status of being proven in a test. No more now! Researchers from Stanford University School of Medicine have devised a blood based test that...
Post
Experimental drug shows promise for genetic form of ALS
by American Academy of Neurology An early stage trial of an investigational therapy for amyotrophic lateral sclerosis (ALS) suggests that people could tolerate the experimental drug and, in exploratory results, the experimental drug was linked to possible slower progression in people with a genetic form of the disease caused by mutations in a gene called superoxide dismutase 1 (SOD1). The preliminary study released today will...
Post
Researchers identify 20 novel gene associations with bipolar disorder
by The Mount Sinai Hospital In the largest study of its kind, involving more than 50,000 subjects in 14 countries, researchers at the Icahn School of Medicine at Mount Sinai and more than 200 collaborating institutions have identified 20 new genetic associations with one of the most prevalent and elusive mental illnesses of our time—bipolar disorder. The study is reported in the May...