JOHNS HOPKINS MEDICINE When young athletes experiences sudden cardiac death as they run down the playing field, it’s usually due to arrhythmogenic cardiomyopathy (ACM), an inherited heart disease. Now, Johns Hopkins researchers have shed new light on the role of the immune system in the progression of ACM and, in the process, discovered a new...
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Study reveals fundamental insight into how memory changes with age
KING’S COLLEGE LONDON New research from King’s College London and The Open University could help explain why memory in old age is much less flexible than in young adulthood. Through experiments in mice the researchers discovered that there were dramatic differences in how memories were stored in old age, compared to young adulthood. These differences,...
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BARseq builds a better brain map
COLD SPRING HARBOR LABORATORY Cold Spring Harbor Laboratory Professor Anthony Zador has taken the next step in his quest to solve exactly how the brain is wired. Zador, a neuroscientist whose lab studies how the brain’s circuitry mediates and controls complex behaviors, set out about 10 years ago to map three pillars of brain function:...
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Researchers identify targeted therapy that can help children with deadly nerve cancer
by The Mount Sinai Hospital Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell. Neuroblastoma is one of the most common and aggressive pediatric nervous system tumors and generally...
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Three reasons you have neck pain – and why ‘bad posture’ probably isn’t one of them
by Christian Worsfold, The Conversation If you suffer from neck pain, you’re not alone. Spinal pain is one of the leading causes of disability worldwide and its occurrence has increased dramatically over the past 25 years. While most episodes of neck pain are likely to get better within a few months, half to three-quarters of...
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Molecular control of neurotransmitter linked to autism described
Many neurodevelopmental disorders such as epilepsy, schizophrenia, and autism have been linked to disruption of the key neurotransmitter GABA, but the underlying causes of the disruptions have been difficult to pinpoint. In two new papers published Oct. 15 in Science Signaling, researchers from Yale, France, Japan, and the United Kingdom have zeroed in on a...
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Chip to Evaluate Health of Immune System from Blood Sample
OCTOBER 17TH, 2019 MEDGADGET EDITORSDIAGNOSTICS, MEDICINE, PATHOLOGY, PUBLIC HEALTH, SPORTS MEDICINE Knowing how well a patient’s immune system is functioning may be very useful in diagnosing a disease and guiding the course of therapy. Researchers from Nanyang Technological University in Singapore are making this a reality, having developed a hybrid chip that assesses the health...
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Cell family trees tracked to discover their role in tissue scarring and liver disease
Posted Today Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions. The research by academics from the Universities of Edinburgh and Bristol and funded by the Wellcome Trust and Medical Research Council is published in Nature Communications. The distinguishing feature of...
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How Proinsulin Misfolding is a Prelude to Type 2 Diabetes
Posted Today An astounding 86 million people in the United States have prediabetes, a condition marked by elevated blood sugar that gives rise to type 2 diabetes. Of these individuals, 90% don’t know that they have the condition, which increases their risk of developing heart disease and stroke. When an individual has prediabetes, the increased...
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SYSTEM AIMS TO ALERT YOU ABOUT DRUG-DRUG INTERACTIONS
OCTOBER 17TH, 2019POSTED BY MATT SWAYNE-PENN STATE A machine learning system may be able to warn doctors and patients about possible negative side effects from drug-drug interactions. The more medications a patient takes, the greater the likelihood that interactions between those drugs could trigger negative side effects, including long-term organ damage or even death. For the study, researchers designed an algorithm...