POSTED BY KATE MCALPINE-MICHIGAN Erin Evke demonstrates how the kirigami cut pattern opens into a lacework. (Credit: Levi Hutmacher/Michigan Engineering) A new sensor patch could bring the assessment of human joints into the 21st century, researchers report. The patch uses electronic sensors to understand the functional range of motion as opposed to today’s static measurements. Kirigami, the Japanese art...
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Scientists liken mitochondria to Tesla battery packs
By Catharine Paddock, Ph.D. Fact checked by Isabel Godfrey New research reveals that mitochondria, the tiny powerhouses that live inside cells and give them energy, work more like a Tesla battery pack than the kind of battery that you put in a flashlight. Apart from red blood cells, all cells in the human body contain...
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New universe of miniproteins is upending cell biology and genetics
By Mitch LeslieOct. 17, 2019 , 2:00 PM Mice put human runners to shame. Despite taking puny strides, the rodents can log 10 kilometers or more per night on an exercise wheel. But the mice that muscle biologist Eric Olson of the University of Texas Southwestern Medical Center in Dallas and colleagues unveiled in 2015...
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A new study says there could be a surprising consequence to losing weight later in life
By Katie Hunt, CNN Updated 6:27 AM ET, Thu October 17, 2019 (CNN)Being overweight is linked to many health problems, and shedding some pounds is often presented as the best way to avoid them, no matter your age. But it’s not quite that simple, according to a study published Wednesday in The BMJ that examines...
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The application of resveratrol to mesenchymal stromal cell-based regenerative medicine
Chenxia Hu & Lanjuan Li Stem Cell Research & Therapy volume 10, Article number: 307 (2019) Abstract Currently, the transplantation of mesenchymal stromal cells (MSCs) has emerged as an effective strategy to protect against tissue and organ injury. MSC transplantation also serves as a promising therapy for regenerative medicine, while poor engraftment and limited survival rates are major obstacles for...
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A compound effective to chemotherapy-resistant cancer cells identified
HOKKAIDO UNIVERSITY A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity. Despite longstanding and earnest endeavors to develop new remedies, the prognosis of most glioblastoma patients undergoing chemotherapies and radiotherapies remains poor. Glioblastoma, a malignant glioma, has a median...
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When added to gene therapy, plant-based compound may enable faster, more effective treatments
Scripps Research team finds that a nontoxic molecule closely related to resveratrol can overcome barriers to delivering gene therapy into stem cells. SCRIPPS RESEARCH INSTITUTE LA JOLLA, CA – Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia. These diseases, which...
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A simpler way to make some medicines
Chemists find new way of creating the building blocks of many drugs OHIO STATE UNIVERSITY COLUMBUS, Ohio – Organic chemists at The Ohio State University have figured out how to synthesize the most common molecule arrangement in medicine, a scientific discovery that could change the way a number of drugs – including one most commonly used to...
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Parasite paralysis: A new way to fight schistosomiasis?
MORGRIDGE INSTITUTE FOR RESEARCH MADISON — Scientists at the Morgridge Institute for Research have isolated a natural chemical that acts as a potent kryptonite against schistosomes, the parasitic worms that burrow through human skin and cause devastating health problems. A research team led by Morgridge investigator Phillip Newmark reported in today’s (Oct. 17, 2019) issue...
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Study shows mouse cerebellum quite different from human
by Bob Yirka , Medical Xpress An international team of researchers has found that the mouse cerebellum may not be a good model for the human cerebellum in brain studies. In their study published in the journal Science, the group describes their comparison study that involved the human, mice and macaque cerebellums as they developed....