by Heidelberg University How does the brain translate information from the outside world into something we remember? An international team of researchers working in the Human Brain Project have zoomed in on the neuronal circuits in the striatum, a brain structure involved in memory, behavior and reward learning. The findings, published in the PLOS Computational...
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Genetic ‘fingerprint’ may ID breast cancer patients likely to benefit from potentially toxic chemo, study finds
by Krista Conger, Stanford University Medical Center Women with early-stage breast cancer that has a specific pattern of gene expression are more likely than others to benefit from treatment with a class of common but potentially harmful chemotherapy drugs called anthracyclines, according to researchers at the Stanford University School of Medicine. Identifying these women is...
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Nanoparticles Cross Blood-Brain Barrier to Treat Stroke
NOVEMBER 7TH, 2019 MEDGADGET EDITORS CRITICAL CARE, EMERGENCY MEDICINE, MATERIALS, MEDICINE, NANOMEDICINE, NEUROLOGY, NEUROSURGERY Ischemic strokes can cause havoc in the brain, but early and properly directed treatment can mitigate a lot of damage. While there are a number of options to unclog blocked arteries, the potential to provide additional drug therapy remains mostly unexplored...
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New technique to identify a common cause for diseases related to thrombotic microangiopathies for which there is a treatment
There is a group of diseases the symptoms of which have a common origin: a lesion in the endothelial tissue that covers the inside of the blood vessels. This lesion, called TMA (Thrombotic Microangiopathy), causes a migration of platelets to cover the wound. Smaller blood vessels collapse, producing a series of symptoms such as anaemia,...
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Early Results from First-In-U.S. Trial of CRISPR-Edited Immune Cells for Cancer Patients Suggest Safety of Approach
Abramson Cancer Center researchers to present initial safety data after treating three patients. Genetically editing a cancer patient’s immune cells using CRISPR/Cas9 technology, then infusing those cells back into the patient appears safe and feasible based on early data from the first-ever clinical trial to test the approach in humans in the United States. Researchers...
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ACETAMINOPHEN DURING PREGNANCY LINKED TO HIGHER RISK OF ADHD, AUTISM LATER
Exposure to acetaminophen in the womb may increase a child’s risk for attention deficit hyperactivity disorder or autism spectrum disorder, according to a new study. Researchers analyzed data from the Boston Birth Cohort, a 20-year study of early life factors influencing pregnancy and child development. They found that children whose cord blood samples contained the...
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‘NANOPIECES’ MAY DELIVER DRUGS TO TREAT INCURABLE BONE CANCER
Researchers have used nanotechnology to identify a potentially groundbreaking treatment for an aggressive bone cancer that has proven disappointingly unresponsive to existing therapies, a new study shows. The new approach to treating chondrosarcoma, a rare cancer that typically afflicts adults and has poor survival rates, appears in the journal Molecular Cancer Therapeutics. The research, using...
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Researchers report new insights into Parkinson’s disease-related mortality
by IOS Press By following a group of newly diagnosed patients with Parkinson’s disease (PD) for a decade or more, researchers have been able to identify several factors never before reported that appear to be associated with higher mortality rates in PD patients compared to the general population. As reported in the Journal of Parkinson’s...
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Stress hormone helps control the circadian rhythm of brain cells
by University of Copenhagen As day turns into night, and night turns into day, the vast majority of living organisms follow a fixed circadian rhythm that controls everything from sleep needs to body temperature. This internal clock is found in everything from bacteria to humans and is controlled by some very distinct hereditary genes, known...
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Critics challenge study’s finding that water fluoridation damages children’s IQ
by Catherine Carstairs, The Conversation A recent study showed that community water fluoridation was associated with lower IQ scores in young children. Opponents of water fluoridation jumped on the study, claiming that it confirms the dangers of fluoride on the developing brain. Since then, a number of critics have pointed out that the differences in...