Aggressive forms of breast cancer often manipulate the immune response in their favor. This manipulation is revealed in humans by the same immunological “signature” as in mice. This is shown by a study carried out by scientists from the University of Bonn together with Dutch colleagues. Their method makes it possible to obtain an indication of the prognosis of the disease...
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Scientists Demonstrate Direct Brain-to-Brain Communication in Humans
Work on an “Internet of brains” takes another step By Robert Martone on October 29, 2019 We humans have evolved a rich repertoire of communication, from gesture to sophisticated languages. All of these forms of communication link otherwise separate individuals in such a way that they can share and express their singular experiences and work...
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Seeking better treatment for ALS, Lou Gehrig’s disease
COLD SPRING HARBOR LABORATORY There is currently no cure for amyotrophic lateral sclerosis (ALS). But new research could open up avenues for better diagnosis and more effective treatment. The study, led by Cold Spring Harbor Laboratory Associate Professor Molly Gale Hammell, analyzed the role proteins called TDP-43 play in ALS, also known as Lou Gehrig’s...
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Avocados may help manage obesity, prevent diabetes
UNIVERSITY OF GUELPH Your guacamole may hold the key to managing obesity and helping delay or prevent diabetes, according to a new study by a University of Guelph research team. For the first time, researchers led by Prof. Paul Spagnuolo have shown how a compound found only in avocados can inhibit cellular processes that normally...
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New gene therapy for epilepsy provides on-demand release of endogenous substance
Preclinical study shows long-term suppression of seizures CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN Teams of researchers from Charité – Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having...
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New research suggests proton radiation can benefit pts with challenging liver tumors
by American Society for Radiation Oncology Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma (HCC), a common but often fatal type of liver cancer for which there are limited treatment options. One study (Sanford et al.) suggests that proton radiation, compared to traditional photon radiation, can extend overall survival with reduced toxicity. A second study (Hsieh et al.) identifies predictors for...
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Reading the Brain’s Map: Coordinated Brain Activation Supports Spatial Learning and Decision-Making
NIH-supported study finds that spatial “replay” in neurons may help rats learn how to navigate toward goals Specialized brain activation “replays” the possible routes that rats can take as they navigate a space, helping them keep track of the paths they’ve already taken and choose among the routes that they can take next, according to...
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Scientists identify new potential treatment pathway for cardiovascular disease
by University of Sheffield Scientists from the University of Sheffield have identified a new potential treatment pathway for cardiovascular disease. Their research has shown for the first time that a protein expressed in a subset of immune cells contributes towards the build-up of fatty deposits in arteries, which leads to cardiovascular disease. These fatty deposits...
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Enter the exosome: WVU researcher studies how cancer and immune cells communicate
WEST VIRGINIA UNIVERSITY Cells can’t text each other the way we can, but they can still communicate. One way they send each other messages is through exosomes–tiny, spherical “packages” of information they emit. David Klinke, a researcher with the West Virginia University School of Medicine and Cancer Institute, is deciphering the contents of exosomes that...
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Liver damage from drinking may one day be REVERSIBLE: Scientists are developing a drug to undo tissue scarring in lung and liver disease
Scar tissue forms in the place of healthy tissue in organs This process is called cirrhosis in the liver and fibrosis in the lungs Its a hallmark of liver and lung diseases triggered by excessive drinking and smoking This damage is currently irreversible, incurable and can prove fatal But Mayo Clinic researchers discovered they can block two proteins to tell scar tissue precursors to do the opposite, removing and breaking down...