by Bob Yirka , Medical Xpress A team of researchers affiliated with several institutions in the U.S. and Australia (and sponsored by pharmaceutical company Amgen Research) has found that a drug they optimized to target a protein produced due to mutations in the genome was able to shrink some tumors in mice and humans. In...
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Bariatric surgery linked to reduced risk for skin cancer
(HealthDay)—For individuals with obesity, bariatric surgery is associated with a reduced risk for skin cancer, including melanoma, according to a study published online Oct. 30 in JAMA Dermatology. Magdalena Taube, Ph.D., from the University of Gothenburg in Sweden, and colleagues examined the correlation of bariatric surgery with skin cancer and melanoma incidence in the Swedish...
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Common sites of bone erosion in rheumatoid arthritis ID’d on US
(HealthDay)—Joint recesses with bone erosion are more likely to exhibit greater severity of joint inflammation on ultrasound (US) examination, according to a study published online Oct. 25 in the Journal of Clinical Ultrasound. York Kiat Tan, from Singapore General Hospital, and colleagues used an extended 36-joint sonographic examination in 30 patients with rheumatoid arthritis to...
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Study aims at boosting antitumoral activity of compound extracted from an Amazon plant
Scientists plan to develop a modified strain of U. guianensis and use its own metabolism to scale up the production of therapeutic compounds FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest....
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How Deep Sleep May Help The Brain Clear Alzheimer’s Toxins
Heard on All Things ConsideredJON HAMILTON The brain waves generated during deep sleep appear to trigger a cleaning system in the brain that protects it against Alzheimer’s and other neurodegenerative diseases. Electrical signals known as slow waves appear just before a pulse of fluid washes through the brain, presumably removing toxins associated with Alzheimer’s, researchers...
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A new material for regenerative medicine capable to control cell immune response
Scientists of Tomsk Polytechnic University jointly with the University of Montana (USA) proposed a new promising material for regenerative medicine for recovery of damaged tissues and blood vessels. TOMSK POLYTECHNIC UNIVERSITY In this case, such an irritant is a regenerative material. According to scientists, the proposed solution is a simpler way to control the immune...
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U. Iowa team is developing new delivery tools for gene editing
Engineered peptides provide efficient, non-toxic delivery of gene-editing proteins to airway cells UNIVERSITY OF IOWA HEALTH CARE News of advances in gene-editing technology raises the prospect of actually using this approach to treat disease in patients. But one of the hurdles that remains is how to deliver these tools to the right cells in the patients safely and efficiently. Scientists led by University of Iowa researcher Paul...
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Researchers find new signaling systems in human cells
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES The human cell has a wide variety of receptors on its surface that many molecules and therapeutic drugs can bind to in order to activate signals inside the cell to regulate different physiological functions. GPCRs are the largest – and a very important – family of receptors...
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Microscopic Donuts Swim On Their Own to Deliver Therapies Inside Body
OCTOBER 31ST, 2019 MEDGADGET EDITORS MEDICINE, NANOMEDICINE While there has been a great deal of work on a variety of micro- and nanoparticles that can deliver drugs and other therapies within the body, compared with bacteria they’re extremely rudimentary in how they can move within the body. Most are simply carried along by the blood...
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Advanced microscopy reveals unusual DNA structure
Sandia scientist pushes technology’s limits to see fundamental feature of stretched S-DNA An advanced imaging technique reveals new structural details of S-DNA, ladder-like DNA that forms when the molecule experiences extreme tension. This work conducted at Sandia National Laboratories and Vrije University in the Netherlands provides the first experimental evidence that S-DNA contains highly tilted...