by eLife Scientists have revealed how common respiratory bugs that cause serious infections in people with cystic fibrosis interact together, according to a new study in eLife. The results provide insights into how bacterial pathogens wrestle each other for territory that could open avenues for new antibacterial treatments. Studies of microbes from mouths, intestines, chronic...
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Common muscle relaxant causes severe confusion in patients with kidney disease
UNIVERSITY OF WESTERN ONTARIO One in 25 patients with very low kidney function were admitted to hospital with severe confusion and other cognitive-related symptoms a few days after being prescribed a common muscle relaxant. A new study from ICES Western, Western University and Lawson Health Research Institute has shown that patients with kidney dysfunction who...
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Exercise levels predict lifespan better than smoking, medical history
Wearable activity trackers may pave the way for a better method to predict short term death risk, suggests a new study, which found that exercise data was more accurate than other risk factors, such as smoking and medical history. New research suggests that physical activity levels might be a better predictor of lifespan than medical...
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Low-dose oral prednisolone substantially improves pain and function in hand OA
by American College of Rheumatology Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis (Abstract #1760). Osteoarthritis (also known as OA) is a common joint disease that most often affects middle-age to elderly...
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ADA2 is a specific biomarker for MAS in systemic JIA
by American College of Rheumatology According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA) (Abstract #920). About one child in every 1,000 develops some...
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Methotrexate reduces joint damage progression over placebo in erosive hand OA
by American College of Rheumatology According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems...
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Live zoster vaccine safe and effective for people taking TNF inhibitors
AMERICAN COLLEGE OF RHEUMATOLOGY ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications (Abstract # 824). In healthy individuals, excess TNF in the blood is...
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Best practice treatment guidelines help doctors identify, treat vaping-associated lung injuries
INTERMOUNTAIN MEDICAL CENTER As the outbreak of lung injuries and deaths associated with e-cigarettes, or vaping, continues to spread across the U.S., researchers at Intermountain Healthcare in Salt Lake City have effectively developed a best practice treatment guide to quickly identify and treat patients who develop the new and potentially fatal respiratory injury, according to...
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Video Game Uses Brain Wave Monitoring to Treat ADHD
MEDGADGET EDITORS | NEUROLOGY, PEDIATRICS, PSYCHIATRY While there are a number of drugs to treat Attention Deficit Hyperactivity Disorder (ADHD), they can have some pretty serious side effects. Researchers in Singapore at the country’s Institute of Mental Health (IMH), Duke-NUS (National University of Singapore) Medical School, and A*STAR (Agency for Science, Technology and Research), have developed a...
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Why Choose Competitive ELISA or Sandwich ELISA?
Sponsored Content by St John’s Laboratory Enzyme Linked Immunosorbent Assay (ELISA) is a basic, sensitive, reliable, and efficient analytical method employed for the quantification and detection of protein biomarkers in immunoassays.1 How Does an ELISA Work? The ELISA method is established on the strength of the interaction between an antigen and an antibody, frequently called the binding specificity and...