A new smart bandage design could eventually heal chronic wounds by getting under a patient’s skin — using an array of tiny needles to deliver therapeutic drugs directly to the still-living but damaged tissue. Developed at the University of Connecticut and University of Nebraska–Lincoln, the 3D-printed prototype consists of a polymer bandage equipped with millimeter-scale...
ATTENTION TRAINING MAY EASE TEEN ANXIETY DISORDERS
FRED MAMOUN-YALE A simple computer-based program known as attention training may offer relief to teens with an anxiety disorder, according to a new study. Researchers discovered major reductions in anxiety among 64 youths after just four twice-weekly sessions of the attention training program. All the youths had diagnosed anxiety disorders and had completed cognitive behavior...
Revving habits up and down, new insight into how the brain forms habits
by Dartmouth College An illustration of the dorsolateral striatum shown as a cross-section. The blue shading shows the area of the brain that had the optogenetic receptors, and the black dots show where the placements were for light delivery. Credit: study co-authors Each day, humans and animals rely on habits to complete routine tasks such...
A New Era in the Treatment of Atopic Dermatitis
M. Le Bwohl DISCLOSURES The British Journal of Dermatology. 2019;181(4):658 We are on the verge of major breakthroughs in the treatment of atopic dermatitis. We already have many topical therapies, and newer ones in the form of aryl hydrocarbon receptor modulating agents and topical Janus kinase (JAK) inhibitors are on the way.[1,2] Injectable biologic therapies...
Old weapon, new target: Dasatinib against angioimmunoblastic T-cell lymphoma
Researchers from the University of Tsukuba show that angioimmunoblastic T-cell lymphoma (AITL) is dependent on T-cell receptor (TCR) signaling and that dasatinib, a multi-kinase inhibitor that targets the TCR pathway, may improve treatment outcomes UNIVERSITY OF TSUKUBA Tsukuba, Japan – Angioimmunoblastic T-cell Lymphoma (AITL) is an intractable form of non-Hodgkin lymphoma with a bleak prognosis....
Inhalation therapy shows promise against pulmonary fibrosis in mice, rats
NORTH CAROLINA STATE UNIVERSITY A new study from North Carolina State University shows that lung stem cell secretions – specifically exosomes and secretomes – delivered via nebulizer, can help repair lung injuries due to multiple types of pulmonary fibrosis in mice and rats. The work could lead to more effective, less invasive treatment for human...
Artificial intelligence can scan doctors’ notes to distinguish between types of back pain
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE (New York, NY – February 27, 2020) -Mount Sinai researchers have designed an artificial intelligence model that can determine whether lower back pain is acute or chronic by scouring doctors’ notes within electronic medical records, an approach that can help to treat patients more accurately,...
Could new discovery play a role in diagnosing Alzheimer’s earlier?
Discovered in mice and confirmed in human samples, scientific team become the first to observe how a characteristic of the Presenilin1 gene means it could be used as a biomarker for Alzheimer’s TAYLOR & FRANCIS GROUP Scientists have detected that a previously overlooked gene behavior could potentially lead to a new way to diagnose Alzheimer’s...
New immunotherapeutic strategy shows promise in eradicating infectious biofilms
Communities of bacteria known as biofilms are notorious for forming on implanted medical devices and tissues in the body, where they give rise to chronic, sometimes life-threatening infections TEMPLE UNIVERSITY HEALTH SYSTEM Communities of bacteria known as biofilms are notorious for forming on implanted medical devices, such as catheters and prosthetics, and on tissues in...
Celiac disease might be cured by restoring immune tolerance to gliadin
UNIVERSITY OF HELSINKI Celiac disease affects 0.3-2.4% of people in most countries world-wide, and approx. 2% in Finland. Celiac patients suffer from a variety of symptoms, typically intestinal complaints, such as diarrhea, but are often symptom-free. Immunologist Tobias Freitag co-developed and tested nanoparticles containing gliadin for the immunomodulatory treatment of celiac disease in Professor Seppo...