New research from the University of Sheffield into stem cells could help make regenerative medicine safer Regenerative medicine involves using pluripotent stem cells to repair damaged or diseased tissues in the body The new research has suggested ways to reduce the likelihood of mutations occurring in these cells when cultured. Research from the University of...
Vitamin B3 revitalizes energy metabolism in muscle disease
An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effect in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments. Vitamin B3 forms have recently emerged as potent boosters of energy metabolism in rodents. These vitamins...
Local inflammatory cells are characteristic for advanced multiple sclerosis
In the brains of people that suffer from long-term multiple sclerosis (MS), inflammatory cells are not entering the brain via the bloodstream anymore. Instead, the cells arise from local memory cells in the brain. Nina Fransen and her colleagues of the Netherlands Institute for Neuroscience show this in a recently published article in the scientific...
Critical window for re-infection with HIV after stem cell transplantation
Some people with HIV need to undergo an allogeneic stem cell transplantation in order to treat different types of blood cancer. Most of the patient’s immune cells are eliminated during these transplantations. Stem cells from a healthy donor are then used to replace the patient’s damaged bone marrow and restore their immune system. “In the...
New imaging tool helps researchers see extent of Alzheimer’s early damage
New imaging technology allows scientists to see the widespread loss of brain synapses in early stages of Alzheimer’s disease, a finding that one day may help aid in drug development, according to a new Yale University study. The research, published May 13 in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, compared the density...
New treatment extends lives of people with most common type of liver cancer
by University of California, Los Angeles For the first time in over a decade, scientists have identified a first-line treatment that significantly improves survival for people with hepatocellular carcinoma, the most common type of liver cancer. Researchers found that the combination of atezolizumab, an immunotherapy drug that boosts the body’s natural defenses, and bevacizumab, an...
Type 2 diabetes linked to worse cognitive performance after a stroke
by American Heart Association People with Type 2 diabetes, but not those with prediabetes, had worse cognitive performance three to six months after a stroke than those with normal fasting blood sugar levels, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association....
Once a coronavirus vaccine exists, this researcher’s mailable patch could deliver it to millions
by Greg Weatherford, Virginia Commonwealth University Someday, hundreds of millions of vaccinations against the coronavirus that causes COVID-19 could show up in people’s mailboxes and be applied as simply as slapping on a Band-Aid. That’s the vision of Guizhi “Julian” Zhu, Ph.D., at the Virginia Commonwealth University School of Pharmacy. Zhu, an assistant professor in...
Brain disease treatment shows promising signs
by Michael Addelman, University of Manchester Early results for a potentially revolutionary brain disease therapy given under compassionate use to a two-year-old has shown promise, a University of Manchester scientist will tell an international conference on Wednesday (13 May). Professor Brian Bigger will tell the American Society of Gene & Cell Therapy that the safety...
Scientists develop technique for more accurate brain diagnoses
by South Ural State University, South Ural State University Scientists of South Ural State University have developed a technique to identify the functional state of the brain with absolute accuracy. The results of the study will contribute to medical and physiological diagnostics. Electroencephalography is a study of the brainbased on the recording of its bioelectric...