by American Physiological Society Readily available dental mouthwashes have the potential to destroy the lipid envelope of coronaviruses, combating virus replication in the mouth and throat. The findings are presented in a new review article published today in Function, concluding that there is an urgent need to test the effectiveness of this approach in clinical...
Month: <span>May 2020</span>
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‘Cell pores’ discovery gives hope to millions of brain and spinal cord injury patients
by Aston University Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year. The breakthrough in treating such injuries—referred to as central nervous system (CNS) edema—is thought to be hugely significant because current options are limited to putting patients in...
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Repurposed drug helps obese mice lose weight, improve metabolic function
by NIH/National Institute on Aging An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized body weight and reversed metabolic damage in obese middle-aged mice of both sexes. The international study was led by researchers at the National Institute on Aging (NIA),...
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Researchers find one-two punch may help fight against Salmonella
by McMaster University McMaster University researchers have discovered a combination punch to treat drug-resistant infections that is showing promise based on testing in mice. Researchers found that a natural product called dephostatin is an effective partner for the antibiotic colistin in treating infections caused by the bacteria Salmonella. Colistin is considered a last-resort antibiotic for...
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Researchers identify most powerful gene variant for height known to date
by Jake Miller, Harvard Medical School A team of researchers from Harvard Medical School, Brigham and Women’s Hospital, Socios En Salud, and the Broad Institute at Harvard and MIT report they have identified the single largest genetic contributor to height known to date. The findings, published May 13 in Nature, are based on an analysis...
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Uncovering how ‘dark matter’ regions of the genome affect inflammatory diseases
by Babraham Institute A study led by researchers at the Babraham Institute in collaboration with the Wellcome Sanger Institute has uncovered how variations in a non-protein coding ‘dark matter’ region of the genome could make patients susceptible to complex autoimmune and allergic diseases such as inflammatory bowel disease. The study in mice and human cells...
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Addition of zinc may benefit some being treated for COVID-19
(HealthDay)—For hospitalized patients with COVID-19, the addition of zinc sulfate to hydroxychloroquine and azithromycin may improve some outcomes, according to a study not yet peer reviewed and posted on medRxiv.org. Philip M. Carlucci, from New York University Grossman School of Medicine in New York City, and colleagues collected data from electronic medical records for COVID-19...
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How blocking iron drives the lung immune system to control infection
by Ciara O’shea, Trinity College Dublin Although COVID-19 commands the headlines today, tuberculosis (TB) remains the biggest infection killer in the world and multiple drug resistant TB, which does not respond to regular antibiotics, continues to be a major threat to global health. TB is caused by bacteria (Mycobacterium tuberculosis) that most often affect the...
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New hope for ACL injuries: Adding eccentric exercises could improve physical therapy outcomes
by Laura Bailey, University of Michigan People with anterior cruciate ligament injuries can lose up to 40% of the muscle strength in the affected leg––with muscle atrophy remaining a big problem even after ACL reconstruction and physical therapy. Now, a new University of Michigan study challenges conventional wisdom about which exercises are most beneficial during...
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Meet the ‘psychobiome’: the gut bacteria that may alter how you think, feel, and act
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