by University of Bristol With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections. Candida albicans, a well-known yeast usually seen in the mouth, skin, gut and vagina, is reported to form biofilms...
Blood test helped detect cancer before symptoms, study finds
by Marilynn Marchione For the first time, a blood test has been shown to help detect many types of cancer in a study of thousands of people with no history or symptoms of the disease. The test is still experimental. Even its fans say it needs to be improved and that Tuesday’s results are not...
Scientists recreate DNA damage caused by toxins from smoking
CREDIT: PHIL ROBERTS Researchers from the University of York have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking. The causes of bladder cancer remain largely unknown, however smoking is seen as the main risk factor...
Study among first to explore link between antidepressants during pregnancy and child development in kindergarten
by University of Manitoba Children whose mothers had depression and took serotonergic antidepressants during pregnancy have an increased risk of deficits in language and cognition, compared to children of mothers who had depression during pregnancy and did not take antidepressants, according to findings in a new University of Manitoba study published today in Pediatrics, the...
Clinical trial in COVID-19 patients tests anti-inflammatory drug
by The Scripps Research Institute An anti-inflammatory drug developed at Scripps Research 25 years ago is now being tested as a way to prevent acute respiratory distress in patients with COVID-19, the pandemic disease caused by the novel coronavirus. The drug, a monoclonal antibody now owned by the pharmaceutical company Implicit Bioscience, is planned to...
Schizophrenia related to abnormal fatty metabolism in the brain
by RIKEN Levels of the sphingolipid S1P were lower than normal in the corpus callosum (white matter) in the postmortem brains of people with schizophrenia. Credit: RIKEN Researchers at the RIKEN Center for Brian Science (CBS) in Japan have discovered a deficiency in the brains of people with schizophrenia that could lead to the development...
Nanotechnology might help fight deadly ‘cytokine storm’ of COVID-19
by E.j. Mundell, Healthday Reporter For many COVID-19 patients battling for their lives in the ICU, a runaway immune system response—known as a “cytokine storm”—is their primary foe. Doctors have few tools to help tame this hyperinflammatory condition, but early research is suggesting that nanotechnology might safely deliver drugs to affected tissues, quieting the storm....
Radboudumc researchers publish new insights into COVID-19
Researchers at the Radboud university medical center seem to have found an essential mechanism in the disease process of COVID-19, which has so far been overlooked. If the insight is correct, it probably has important consequences for the treatment of the disease. In an international collaborative effort it is now being investigated whether the new...
Scientists explore links between genetics, gut microbiome and memory
A new study is among the first to trace the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population. While tantalizing links between the gut microbiome and brain have previously been found, a team of researchers from two U.S. Department of Energy...
Arteries respond in opposite ways for males and females – pharmaceutical
CREDIT: COPYRIGHT UC REGENTS/UC DAVIS HEALTH A protein known to expand blood vessels — key to controlling conditions like high blood pressure — actually has different functions in males and females, new UC Davis Health research shows. Conducted using arterial cells from mice, the study is the first to identify sex-based distinctions in how the...