By Rich Haridy May 18, 2020 South Korean researchers have shown a stem-cell-based topical solution can regrow hair in both male and female subjects with common pattern baldness. The small, randomized, placebo-controlled trial found the treatment both safe and effective, with larger trials hoped to validate the results in more diverse populations. The most common...
Potential new treatment approach to fatal COVID-19
By Sally Robertson, B.Sc Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19). The scientists propose that the antiviral and...
‘Cells-Soldiers’ Turned to Be More Resistant Than ‘Cells Combat-Medics’
Researchers from Sechenov University (a Project 5-100 participant) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis – a type of programmed cell death – depends on the type of their activation. It turned out that cells helping tissues to recover from inflammation were more vulnerable. The researchers...
Subcellular chatter regulates longevity
As people get older, they often feel less energetic, mobile or active. This may be due in part to a decline in mitochondria, the tiny powerhouses inside of our cells, which provide energy and regulate metabolism. In fact, mitochondria decline with age not only in humans, but in many species. Why they do so is...
Complement genes add to sex-based vulnerability in lupus and schizophrenia
Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren’s syndrome, according to findings published in the journal Nature. This extends recent work that showed the gene variants could increase risk for schizophrenia. The gene variants are a member of the...
Animal study shows human brain cells repair damage in multiple sclerosis
A new study shows that when specific human brain cells are transplanted into animal models of multiple sclerosis and other white matter diseases, the cells repair damage and restore function. The study provides one of the final pieces of scientific evidence necessary to advance this treatment strategy to clinical trials. “These findings demonstrate that through...
Chemicals often found in consumer products could lead to obesity and fatty liver diseases
While poor nutrition and lack of exercise contribute to obesity, exposure to these compounds could trigger lifelong susceptibility to weight gain, Baylor University researcher says Chemical compounds found in many consumer products could be major contributors to the onset of lipid-related diseases, such as obesity, in humans, according to a Baylor University study. Until recently,...
X-ray experiments zero in on COVID-19 antibodies
As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach – identifying neutralizing antibodies that could be used as a...
HKBU scientists eliminate drug side effects by manipulating molecular chirality
Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects. The approach, which uses a nanostructure fabrication device, can manipulate the chirality of drug molecules by controlling the direction a substrate is rotated within the device, thus eliminating the possible side effects...
Additional genetic cause for non-alcoholic fatty liver disease discovered
In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors. DZD researchers have now discovered new genes that play a role in the development of fatty liver. In humans and mice, respectively, the genes IRGM, Ifgga2 and Ifgga4 are...