Oxidative stress is the result of reactive oxygen species (ROS) generation, and can be damaging to cells and tissues. In a new study, researchers from Osaka University developed a novel dietary silicon (Si)-based antioxidant agent that suppressed the development and progression of kidney failure and Parkinson’s disease in rodents. ROS are generated as a result...
by Dartmouth-Hitchcock Medical Center The development of pancreatic cancer is driven by co-existing mutations in an oncogene involved in controlling cell growth, called KRAS, and in a tumor suppressor gene, called p53. But how these mutations cooperate to promote cancer is unknown. A new study co-led by Steven Leach, MD, Director of Dartmouth’s and Dartmouth-Hitchcock’s...
by Beckman Institute for Advanced Science and Technology Researchers at the GSK Center for Optical Molecular Imaging have developed a new microscope that looks at the different parameters that change during wound healing. They hope to use this technique to understand how skin disorders, such as foot ulcers in diabetic patients and psoriasis, can be...
by University of British Columbia University of British Columbia (UBC) researchers have led an international team in developing a new test to better diagnose different types of ovarian cancer, a tool that could one day guide and improve treatment options for women diagnosed with the most common and deadliest form of the disease. The development...
Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options. Senescence is a form of cellular stress response. In some circumstances it can be harmful, and efforts are under way to develop therapies that target senescent cells. Writing...
By Sally Robertson, B.Sc A study conducted by researchers at Julius-Maximilians-Universität Würzburg has shown that the antidepressant agent fluoxetine may be an effective drug for the early treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among at-risk groups. Jochen Bodem and colleagues found that the selective serotonin reuptake inhibitor (SSRI) fluoxetine significantly inhibited viral...
Far-flung as they were, each was given the same assignment: Examine collections of irregular, blotchy shapes that formed seemingly abstract patterns, then describe what they saw and derive meaning from the muddle. With enough repetition and informed interpretation, surely those patterns could help tease apart what was going on inside their heads. Rorschach tests, right?...
This news or article is intended for readers with certain scientific or professional knowledge in the field. Like finding that needle in the haystack every time, your T cells manage what seems like an improbable task: quickly finding a few invaders among the many imposters in your body to trigger its immune response. T cells...
WALTER AND ELIZA HALL INSTITUTE Structural biology has been used to ‘map’ part of a protein called SMCHD1, explaining how some changes in SMCHD1 cause certain developmental and degenerative conditions. Publishing in the journal Science Signaling, the Walter and Eliza Hall Institute team revealed the structure of the portion of the SMCHD1 protein that is...
UNIVERSITY OF CALIFORNIA – SAN DIEGO Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce. The first data describing this new direction for fighting COVID-19 were published on June...
