by University of Sussex Scientists at the University of Sussex have identified a potential pattern within blood which signals the presence of motor neuron disease; a discovery which could significantly improve diagnosis. Currently, it can take up to a year for a patient to be diagnosed with amyotrophic lateral sclerosis(ALS), more commonly known as motor...
A sugar hit to help destroy cancer cells
by University of Southern California The research team has discovered that akt-type cancer cells, which are common in breast cancer, above, can be killed by a common milk sugar, galactose. Credit: Wikimedia Commons Like any cells in the body, cancer cells need sugar—namely glucose—to fuel cell proliferation and growth. Cancer cells in particular metabolize glucose...
Novel antisense drug shows promise in slowing fatty liver disease
In Phase II trial, treatment inhibited key enzyme, resulting in lowered triglyceride production and slower progression of non-alcoholic fatty liver disease to its more dangerous form: non-alcoholic steatohepatitis UNIVERSITY OF CALIFORNIA – SAN DIEGO Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San...
Loss of lipid-regulating gene fuels prostate cancer spread
JOHNS HOPKINS MEDICINE ANCER CELLS GOBBLE UP LIPIDS. PROSTATE CELLS ARE STAINED WITH OIL-RED O TO DETECT LIPID DROPLETS. OUR WORK SHOWS THAT REDISTRIBUTION OF LIPIDS FROM PROSTATE CANCER MICROENVIRONMENT TRIGGERS INFLAMMATION AND… view more CREDIT: NICK (JIN-YIH) LOW Johns Hopkins Kimmel Cancer Centerresearchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified...
Wearable patch may provide new treatment option for skin cancer
WEST LAFAYETTE, Ind. – Conventional melanoma therapies, including chemotherapy and radiotherapy, suffer from the toxicity and side effects of repeated treatments due to the aggressive and recurrent nature of melanoma cells. Less invasive topical chemotherapies have emerged as alternatives, but their widespread uses have been hindered by both the painful size of the microneedles and...
Could the cure for IBD be inside your mouth?
by University of Michigan While many people put off their regular trips to the dentist, recent research has shown that the consequences of doing so may go beyond cavities and root canals. From heart disease to diabetes, poor oral health is often a reflection of a person’s overall health and may even be the cause...
Virus co-opts immune protein to avoid antiviral defences
by eLife Electron micrographs of hepatitis C virus purified from cell culture. Scale bar is 50 nanometers. Credit: Center for the Study of Hepatitis C, The Rockefeller University. By discovering a trick the hepatitis C virus uses to evade the immune system, scientists have identified a new antiviral defense system that could be used to...
HIV and TB increase death risk from COVID-19, study finds—but not by much
By Linda NordlingJun. 15, 2020 , 4:30 PM Science’s COVID-19 reporting is supported by the Pulitzer Center. CAPE TOWN, SOUTH AFRICA—Living with HIV or active tuberculosis (TB) increases a person’s likelihood of dying from COVID-19, preliminary data from South Africa show. However, the effect is small compared with other known risk factors such as old...
First report of systemic delivery of micro-dystrophin gene therapy in children with DMD
One-year data from the first four patients dosed is published in JAMA Neurology NATIONWIDE CHILDREN’S HOSPITAL Researchers from Nationwide Children’s Hospital have published in JAMA Neurology results from the first four patients treated in the first clinical trial of systemic delivery of micro-dystrophin gene therapy in children with Duchenne muscular dystrophy (DMD) – and initial...
Smartphone app uses voice recordings to detect fluid in the lungs
EUROPEAN SOCIETY OF CARDIOLOGY Sophia Antipolis – 19 June 2020: Voice analysis by a smartphone app identifies lung congestion in heart failure patients, allowing early intervention before their condition deteriorates. The small study is presented today on HFA Discoveries, a scientific platform of the European Society of Cardiology (ESC).1 “Speech is personal and as such,...