by Luxembourg Institute of Health Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating...
Study shows nervous and immune systems ‘need to talk’ for bone repair Photomicrographs from a recent Johns Hopkins Medicine study showing the importance of the peripheral nervous system in bone injury repair. Clockwise from bottom left: (A) Micro computed tomography image showing bone regrowth in mouse skull 14 days after injury (dashed black line is...
Berkeley Lovelace Jr. @BERKELEYJR Coronavirus antibodies may last only two to three months after a person becomes infected with Covid-19, according to a new study published Thursday in Nature Medicine. Researchers in the Wanzhou District of China compared the antibody response of 37 asymptomatic people with that of 37 symptomatic people. The researchers found people...
by Jennifer Michalowski, Cold Spring Harbor Laboratory Illustration of a chandelier cell (on top in red) connecting to a pyramidal neuron (in green on the bottom) on its axonal initial segment (in blue). Credit: CSHL Within the intricate network of cells that make up the brain, chandelier cells stand out for their elaborate, branching structure....
by Whitehead Institute for Biomedical Research The molecular structure of the cancer drug cisplatin causes it to concentrate in tiny non-membrane bound organelles called condensates held together by the protein MED1. By altering other drugs to concentrate in specific condensates, drug developers may be able to improve targeting efficacy in future. Credit: Isaac Klein, Whitehead...
By JULIET ISSELBACHERJUNE 18, 2020 New research untangles the complex code the brain uses to distinguish between a vast array of smells, offering a scientific explanation for how it separates baby powder from bleach, lemon from orange, or freshly cut grass from freshly brewed coffee. A single scent can trigger a complex chain of events...
UCLA engineers have designed a thin adhesive film that could upgrade a consumer smartwatch into a powerful health monitoring system. The system looks for chemical indicators found in sweat to give a real-time snapshot of what’s happening inside the body. A study detailing the technology was published in the journal Science Advances. Smartwatches can already...
An experimental drug that has been shown to improve the function of diseased and aged mitochondria binds to 12 key proteins involved in energy production, researchers at the University of Washington School of Medicine have found. The drug, elamipretide, also called SS-31, has shown promise for treating rare inherited diseases that affect the mitochondria, the...
o defend the body, the immune system makes proteins known as antibodies that latch onto the perceived threat, be it HIV, the new coronavirus or, as is the case in autoimmune disease, part of the body itself. In a new proof-of-concept study in ACS Sensors, researchers describe a new system for detecting antibodies within a...
The findings provide a clear path to uncovering new drugs to control addiction, pain and neurological disorders such as epilepsy and muscle spasticity CREDIT: (ILLUSTRATION BY YEKATERINA KADYSHEVSKAYA/BRIDGE INSTITUTE AT THE USC MICHELSON CENTER FOR CONVERGENT BIOSCIENCE.) As the body goes about its daily business, molecules called neurotransmitters control the level of electrical activity within...
