Scientists explain the role of a certain protein in the generation of cells critical to bone maintenance Chronic bone and joint diseases, such as osteoporosis and rheumatoid arthritis, affect millions of people worldwide, particularly the elderly, degrading their quality of life. An important factor in both of these diseases is the excessive activity of bone-dissolving...
AUGUSTA, Ga. (June 9, 2020) – Particularly in females with untreated hypertension, reducing salt intake to what’s considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report. In the blood of 145 adults with untreated hypertension, the scientists found that, particularly for the females, just six...
Controlling dopamine signalling by targeting the histamine receptor has been shown to be a promising strategy for preventing the progression of Huntington’s disease in mice Scientists have described a potential new therapeutic strategy for slowing down early-stage Huntington’s disease in a new study published today in eLife. The research in mice indicates that targeting the...
by Uppsala University Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The study is published in Genome Biology. The human genome consists of nearly 22,000 genes. Many studies have explored the nearly...
by Westmead Institute for Medical Research PhD student Ratna Wijaya, Professor Golo Ahlenstiel and Dr Scott Read. Credit: The Westmead Institute for Medical Research (WIMR) For the first time, researchers at The Westmead Institute for Medical Research (WIMR) have identified and described a new and unique subset of human cells that are involved in the...
by University of Michigan For children and young adults with Crohn’s disease, steroid-sparing therapies may help reduce the risk of developing a severe and common complication of the inflammatory bowel condition, a new study suggests. About one in three people with Crohn’s disease develop what’s known as a perianal fistula, which can be painful, difficult...
by Goethe University Frankfurt am Main Speaking requires both sides of the brain. Each hemisphere takes over a part of the complex task of forming sounds, modulating the voice and monitoring what has been said. However, the distribution of tasks is different than has been thought up to now, as an interdisciplinary team of neuroscientists...
Muscle stem cells, the reserve stem cell in the skeletal muscles, are responsible for muscle repair after damage. They are the ‘regenerative medicine’ to cure muscle diseases and muscle damage. In a healthy uninjured condition, muscle stem cells are in quiescence, a dormant state, to preserve them. Whenever there is muscle damage, they will wake...
Like any addiction, nicotine dependence warps the brain in elaborate ways—which is why treating it tends not to be as simple as mastering one’s willpower. Even after trying every technique in the toolbox—the support of friends, family, and a great therapist; nicotine patches; prescription drugs—many smokers will sooner or later experience a craving of overpowering...
Neutralizing antibodies are thought to be key to the development of an efficient vaccine against SARS-CoV-2. Researchers at the University of Montreal Hospital Research Centre (CRCHUM) indicate that ensuring their presence over long periods of time might be required. “Our study shows that more than six infected people in ten generated neutralizing antibodies in only...
