by Max Delbrück Center for Molecular Medicine Apolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients, including with polyunsaturated fatty acids—which are building blocks of the membranes surrounding the neurons. In addition, certain unsaturated fatty acids are converted into so-called endocannabinoids. These are endogenous...
by Anna Molin, Karolinska Institutet Knowledge of how human fat tissue is affected by age has long been defined by numerous mouse-based studies. Researchers at Karolinska Institutet in Sweden have now, for the first time, been able to conduct a prospective study on humans that provides novel insights into how our fat cells reduce lipid...
by Sanford Burnham Prebys Medical Discovery Institute An enzyme that blocks the metabolic processes that contribute to the rapid growth and spread of liver cancer has been discovered, according to a study by researchers at Sanford Burnham Prebys and Weill Cornell Medicine. The findings, published in Cancer Cell, could spur development of new therapies for...
Scientists find that reducing levels of uric acid in the blood does not guard against complication in type 1 diabetes. JOSLIN DIABETES CENTER BOSTON – (June 25, 2020) – Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for...
by Cedars-Sinai Medical Center New research from Cedars-Sinai has identified the pathways of neurons that help people retrieve information from memories and use that information to make decisions—a discovery that may aid development of future treatments for memory disorders that accompany certain conditions, like schizophrenia and Alzheimer’s disease. The research, led by Ueli Rutishauser, Ph.D.,...
The study shows that the involvement of certain genes that predispose to cancer also affects the immune system, which could facilitate tumor growth. In the specific case of breast cancer, the involvement of the SH2B3 gene, corresponding to a lymphocyte protein, increases the predisposition to develop cancer. The idea that the immune system “monitors and...
National Institutes of Health investigators and colleagues have discovered that when the immune system first responds to infectious agents such as viruses or bacteria, a natural brake on the response prevents overactivation. Their new study in mBio describes this brake and the way pathogens such as SARS-CoV-2, the virus that causes COVID-19, turn it on....
Computational modeling yields a protein fragment that could bind to coronavirus spike proteins and destroy them. The research described in this article has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts. Using computational models of protein interactions, researchers at the MIT Media Lab and Center for...
Published on ACS Nano, journal of the American Chemical Society, the study opens important perspectives for treatment of diseases such as Alzheimer’s and Huntington’s disease, but also epilepsy, brain trauma and stroke. ISTITUTO ITALIANO DI TECNOLOGIA – IIT CREDIT: IIT-ISTITUTO ITALIANO DI TECNOLOGIA Lecce, 25th June 2020 – Gold nanoparticles have been developed in the...
In the authors’ opinion, this research will help to treat oncology IMMANUEL KANT BALTIC FEDERAL UNIVERSITY CREDIT: IMMANUEL KANT BALTIC FEDERAL UNIVERSITY Scientists from the Immanuel Kant Baltic Federal University (IKBFU) and National University of Science and Technology “MISiS” have studied how magnet nanoparticles affect cancer cells in the human liver. In the authors’ opinion,...
