For decades, poor medication adherence has been recognized as a significant and persistent problem in the healthcare system. Since a report published in 2000 by the U.S. Department of Health and Human Services, numerous studies have shown that up to 50% of patients exhibit varying degrees of non-adherence and non-persistence. Poor adherence and persistence contribute...
AGA does not recommend the use of probiotics for most digestive conditions
New AGA guideline finds that evidence to support use of probiotics to treat digestive diseases is greatly lacking, identifying only three clinical scenarios where probiotics may benefit patients AMERICAN GASTROENTEROLOGICAL ASSOCIATION Bethesda, MD (June 9, 2020) — It is estimated that more than 3.9 million American adults have taken some form of probiotics, with many...
Researchers identify key immune checkpoint protein that operates within T cells
Columbus, Ohio – A new study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Solove Research Institute (OSUCCC – James) has identified a protein within certain immune cells that is required for optimal immune responses to cancer. The findings, reported in the journal Science Advances,...
Convenient spit test helps women assess cancer risk from the comfort of their own homes
First-of-its-kind clinical trial validates remote genetic counseling STAND UP TO CANCER STAND UP TO CANCER, OVARIAN CANCER RESEARCH ALLIANCE, NATIONAL OVARIAN CANCER COALITION LOGOS view more CREDIT: STAND UP TO CANCER, OVARIAN CANCER RESEARCH ALLIANCE, NATIONAL OVARIAN CANCER COALITION (New York) June 01, 2020 – Genetic testing for cancer risk can significantly improve the prevention...
Solubilizer Captisol enables body to absorb authorized COVID-19 drug therapy
RENDERING OF THE MOLECULAR STRUCTURE OF CAPTISOL, THE SOLUBILIZER INVENTED AT THE UNIVERSITY OF KANSAS, WHICH ALLOWS REMDESIVIR TO BE ADMINISTERED TO THE PATIENT. REMDESIVIR WAS RECENTLY AUTHORIZED UNDER AN… view more CREDIT: VALENTINO STELLA, UNIVERSITY DISTINGUISHED PROFESSOR EMERITUS AT KU LAWRENCE — When the Food and Drug Administration issued an emergency-use authorization for the...
Squid studies illuminate neural dysfunction in ALS; suggest new route to therapy
CREDIT: DANIEL COJANU WOODS HOLE, Mass. — Amyotrophic lateral sclerosis (ALS) is one of the most devastating adult-onset neurodegenerative diseases. Patients, including the late actor/playwright Sam Shepard, become progressively weaker and eventually paralyzed as their motor neurons degenerate and die. To find a cure for ALS, which is fatal, scientists need a deeper understanding of...
ASCO 2020: UK-first study shows feasibility of genetic screening for prostate cancer
Genetic screening for prostate cancer in GP surgeries could be effective at picking up otherwise undiagnosed cases of the disease, a new pilot study shows. Researchers ‘barcoded’ men for their genetic risk of prostate cancer by testing each for 130 DNA changes – and gave those at higher risk follow-up checks. Their study found that...
Call for caution for using a CAR-T immunotherapy against Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a hematological malignancy which incidence increases with age, that is biologically, phenotypically, and genetically very heterogeneous. Its treatment uses to combine chemotherapy followed by allogenic Hematopoietic Stem and Progenitor Cells transplant (allo-HSCT), based on the patient’s eligibility, to consolidate complete remission and prevent relapse. Yet, except for a few subgroups,...
Clinicians identify pink eye as possible primary symptom of COVID-19
by University of Alberta Faculty of Medicine & Dentistry A case of pink eye is now reason to be tested for COVID-19, according to University of Alberta researchers. Coughing, fever and difficulty breathing are common symptoms of the illness, but a recent case study involving an Edmonton woman and published in the Canadian Journal of...
PSA screening affords men long-term benefits, study finds
The benefits of the prostate-specific antigen (PSA) test to screen men for prostate cancer may be greater than the harm, according to a study published in the New England Journal of Medicine. Genitourinary cancer specialists from Seattle Cancer Care Alliance, University of Washington School of Medicine, Fred Hutchinson Cancer Research Center, and Weill Cornell Medicine...