Credit: Syracuse University Syracuse, N.Y. – Syracuse University chemistry professor Dr. Robert P. Doyle has developed a new drug lead to treat type 2 diabetes in millions of patients who are seeking to better control their blood sugar without the common side effects of nausea, vomiting, and in select cases, undesired weight loss. Doyle’s research...
Month: <span>July 2020</span>
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A diabetes drug can combat some of the more severe COVID-19 symptoms in women
A diabetes drug called Metformin was found to reduce the fatality rate of women with the coronavirus by as much as 24%. The drug did not appear to have an impact on men with the coronavirus. The coronavirus pandemic may persist for as long as two years without an effective vaccine. Dr. Anthony Fauci recently...
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A potentially crucial drug for fighting COVID-19 awaits new outbreaks to put it to the test
In April, Armand Balboni received an anxious call from Tokyo. On the line was a contact from Fujifilm Toyama, the Japanese multinational, who told him that problems were cropping up with a plan to ship 30,000 tablets of the drug known as favipiravir to Canada for a clinical trial. “It was their head of business...
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Discovery of a novel drug candidate to develop effective treatments for brain disorders
The study published in Chem is fundamental to develop pharmacological drugs for the treatment of core symptoms in Down syndrome, autism and other brain disorders. Researchers aim to create a start-up company with the support of interested investors ISTITUTO ITALIANO DI TECNOLOGIA – IIT THE PROTEIN NKCC1 IS A TRANSPORTER OF IONS IN THE BRAIN;...
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Study finds fatty acid that kills cancer cells
by Washington State University Researchers have demonstrated that a fatty acid called dihomogamma-linolenic acid, or DGLA, can kill human cancer cells. The study, published in Developmental Cell on July 10, found that DGLA can induce ferroptosis in an animal model and in actual human cancer cells. Ferroptosis is an iron-dependent type of cell death that...
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Fat cell hormone boosts potential of stem cell therapy
by Osaka University Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat and muscle cells. But it’s their ability to stimulate the repair of damaged tissue that has captured the interest of researchers worldwide, with MSCs demonstrating therapeutic effects in the treatment of conditions such...
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DRUG SHOWS PROMISE FOR FIGHTING RARE ALS
An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis has shown promise in a phase 1/phase 2 clinical trial, researchers report. The trial indicated that the experimental drug, known as tofersen, shows evidence of safety that warrants further investigation and lowers levels of a disease-causing protein in people with a type of...
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THESE ARE THE BEST AND WORST MATERIALS FOR FACE MASKS
While research has shown masks are effective in reducing the spread of COVID-19, not all masks or mask materials are equally effective, according to new research. “WE KNEW THAT MASKS WORK, BUT WE WANTED TO KNOW HOW WELL AND COMPARE DIFFERENT MATERIALS’ EFFECTS ON HEALTH OUTCOMES.” In a study in the Journal of Hospital Infection,...
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Nanoparticles for Large Gene Therapy to Cure Common Eye Diseases
MEDGADGET EDITORS GENETICS, NANOMEDICINE, OPHTHALMOLOGY Wet age-related macular degeneration and a number of other eye diseases, including congenital conditions, are related to mutated genes that result in blood vessel abnormalities. These can be treated with gene therapy, but delivering genetic material has proven to be difficult when dealing with large gene sequences that are common...
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Scientists discover protective Alzheimer’s gene and develop rapid drug-testing platform
by Queen Mary, University of London A gene has been discovered that can naturally suppress the signs of Alzheimer’s Disease in human brain cells, in research led by Queen Mary University of London. The scientists have also developed a new rapid drug-screening system for treatments that could potentially delay or prevent the disease. The main...