by University of South Florida Three configurations of active sites where inhibitor GC-376 binds with the COVID-19 virus’s main protease (drug target Mpro), as depicted by 3D computer modeling. Credit: Image generated by Yu Chen, University of South Florida Health, using X-ray crystallography As the death toll from the COVID-19 pandemic mounts, scientists worldwide continue...
Age-related impairments reversed in animal model
by University of Bern With age the frequency of adipose tissue eosinophils decreases gradually. This leads to the production of inflammatory mediators, which promote age-related impairments (e.g. frailty and immunosenescence). Eosinophil cell transfers increase the frequency of these cells in adipose tissue and dampen age-related chronic low-grade inflammation. This results in systemic rejuvenation of the...
Common anti-inflammatory drugs can cause more damage than good for runners
Physical exercising is extremely healthy for your body and mind. However, intense exercising is likely to cause some pains and, sometimes, even injuries. Runners often use non-steroidal anti-inflammatories (NSAIDs) to ease post-exercise aches, pains or injuries, but scientists from the Queen Mary’s University London and the University of Birmingham say that this might be a...
Complications from COVID-19 may depend on von Willebrand factor in the blood
ST. PETERSBURG STATE UNIVERSITY Anna Aksenova, a senior research associate at the Laboratory of Amyloid Biology at St Petersburg University, has advanced a hypothesis that the severe course of COVID-19 may be associated with von Willebrand factor. It is one of the main components of the blood coagulation system. As the researcher suggests, the replication...
Asthma and allergies more common in teens who stay up late
EUROPEAN LUNG FOUNDATION Teenagers who prefer to stay up late and wake later in the morning are more likely to suffer with asthma and allergies compared to those who sleep and wake earlier, according to a study published in ERJ Open Research. [1] Asthma symptoms are known to be strongly linked to the body’s internal...
Common hypertension medications may reduce colorectal cancer risk
Hypertension Journal Report AMERICAN HEART ASSOCIATION DALLAS, July 6, 2020 — Medications commonly prescribed to treat high blood pressure may also reduce patients’ colorectal cancer risk, according to new research published today in Hypertension, an American Heart Association journal. Angiotensin converting enzyme inhibitor (ACE-i) or angiotensin II receptor blocker (ARB) medications are prescribed for conditions...
Study spotlights potential culprit in relapses of multiple sclerosis
by Scott Schrage, University of Nebraska-Lincoln A rendering of B lymphocytes, the white blood cells responsible for producing antibodies to fight infections. Recent research led by Nebraska virologists has found that an overabundance of B lymphocytes infected with the Epstein-Barr virus contributed to the recurrence of multiple sclerosis-like symptoms in mice. Credit: Shutterstock A recent...
NIH study finds out why some words may be more memorable than others
Results suggest our brains use internet search engine strategies to remember words and memories of past experiences. Credit: Courtesy of Zaghloul lab, NIH/NINDS. Thousands of words, big and small, are crammed inside our memory banks just waiting to be swiftly withdrawn and strung into sentences. In a recent study of epilepsy patients and healthy volunteers,...
India aims to release indigenous Covid-19 vaccine by Independence Day
Issued on: 04/07/2020 – 11:50 India’s topmost medical research body said that it is attempting to launch the world’s first Covid-19 vaccine on August 15. However, health experts have questioned the short timeline. ADVERTISING The order by Balram Bhargava, director general of the Indian Council of Medical Research (ICMR) on Friday directs 12 hospitals selected...
Antibodies against phosphorylcholine give protection against rheumatic systemic disease
by Karolinska Institutet A novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity, phosphorylcholine (PC), can be associated with protection in inflammatory systemic diseases, including SLE and Sjögren’s syndrome. The results support evidence for a potential treatment by providing antibodies (anti-PC) to patients with these...