Month: <span>July 2020</span>

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New platform prioritizes synergistic drug combinations against SARS-CoV-2
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New platform prioritizes synergistic drug combinations against SARS-CoV-2

By Sally Robertson, B.Sc. Researchers in the U.S. have used a new web-based platform to help identify synergistic and antagonistic drug combinations and their underlying mechanisms of action in the context of coronavirus disease 2019 (COVID-19). The tool, called COVID-KOP, prioritized 73 combinations of 32 drugs as potential treatments for severe acute respiratory syndrome coronavirus...

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Putting genomics into practice to combat common diseases

Genomics carries great expectations: the power to help health-care providers assess and assist their patients in managing their individualized risks for common, serious medical conditions, such as cancer and heart disease. However, how to effectively meld genetic risk assessments into health care is a complex question. Several medical research institutions across the nation, including UW...

New technique in which drugs make bacteria glow could help fight antibiotic resistance
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New technique in which drugs make bacteria glow could help fight antibiotic resistance

A new technique could help reduce antibiotic prescribing by predicting which drugs could be effective in fighting bacteria within minutes. Scientists at the University of Exeter have developed the method, which allows users to see whether a bacterium is likely to respond to antibiotics. The research is currently in early stages of development, and the...

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New, more infectious strain of COVID-19 now dominates global cases of virus

Researchers have shown that a variation in the viral genome of Covid-19 improved its ability to infect human cells and helped it become the dominant strain circulating around the world today. The study, published today in the journal Cell, shows the variation is more infectious in cell cultures under laboratory conditions. The variant, named ‘D614G’,...

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Tiny mineral particles are better vehicles for promising gene therapy

UNIVERSITY OF WISCONSIN-MADISON MADISON, Wis. — University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans. The technology relies on inserting into...

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Sniffing out smell

ew study reveals how the brain organizes information about odors HARVARD MEDICAL SCHOOL The premiere of the movie Scent of Mystery in 1960 marked a singular event in the annals of cinema: the first, and last, motion picture debut “in glorious Smell-O-Vision.” Hoping to wow moviegoers with a dynamic olfactory experience alongside the familiar spectacles...