by The Physiological Society A new study published in the Journal of Physiology has shown that misfolded protein build-up in the gut could contribute to the development of Alzheimer’s-like symptoms in mice. This could suggest a new treatment approach for Alzheimer’s disease that would target the gut before symptoms of cognitive deficits appear in patients....
Using Epo to treat COVID-19
by Max Planck Society Erythropoietin (Epo) is actually a medication for anemia. According to researchers at the Max Planck Institute of Experimental Medicine in Göttingen, the doping agent Epo could also be effective against COVID-19. The growth factor could mitigate severe disease progression and protect patients from long-term neurological effects when the SARS-CoV-2 virus attacks...
Researchers find more precise way to target tumours with anti-cancer drugs
by Adrianna MacPherson, University of Alberta Researchers at the University of Alberta have found a way to deliver anti-cancer drugs with more precision, which could increase the effectiveness of many cancer treatments. U of A oncologist Frank Wuest altered the surface of nanoparticles, which are well suited to deliver drugs, with epidermal growth factor (EGF),...
Location, location, location: Even gut immune response is site-specific
by Julius-Maximilians-Universität Würzburg The pictures show the same stomach organoids: It shows the cell nuclei (blue) and the skeleton of the cell (pink) as a cross-section of the organoids. In grey is the microscopic picture of the organoids. A single organoid here is about a quarter millimeter in size. Credit: Julius-Maximilians-Universität Würzburg, JMU Why is...
Brain imaging can predict Alzheimer’s-related memory loss
by Karolinska Institutet Researchers at Karolinska Institutet have imaged tau protein in the brains of living patients with Alzheimer’s disease. The amount and spread of tau proved a predictor of future memory loss. Brain imaging for measuring tau can be useful both for improving diagnosis and for developing more effective treatments, say the researchers. The...
Laughing gas may bring relief to veterans suffering from PTSD, new study suggests
by University of Chicago Medical Center For military veterans suffering from post-traumatic stress disorder (PTSD), symptoms such as anxiety, anger and depression can have a devastating impact on their health, daily routine, relationships and overall quality of life. A new pilot study by the University of Chicago Medicine and the Stanford University School of Medicine...
The protein that stands between us and autoimmunity
by Osaka University Tet-mediated B cell tolerance Tet2/3-deficient B cells are activated by self-antigen and express exaggerated amount of CD86. Then those B cells stimulate autoreactive CD4+ T cells, resulting in autoimmune response. Credit: Osaka University The immune system is supposed to protect from external microbial invaders, but sometimes it turns its efforts inward, potentially...
Producing a gaseous messenger molecule inside the body, on demand
Method could shed light on nitric oxide’s role in the neural, circulatory, and immune systems. Nitric oxide is an important signaling molecule in the body, with a role in building nervous system connections that contribute to learning and memory. It also functions as a messenger in the cardiovascular and immune systems. But it has been...
Scientists found that the lack of stress hormone contributes to aging
For hundreds and hundreds of years people have tried to stop the aging process. However, their efforts have never yielded any positive results – there is no youth elixir. Even with the latest scientific advancement we cannot stop the damage that time does on our bodies. But now scientists from Saarland University have figured out...
Coronavirus damages the endocrine system
Steroids may offer vital COVID-19 treatment strategy THE ENDOCRINE SOCIETY WASHINGTON–People with endocrine disorders may see their condition worsen as a result of COVID-19, according to a new review published in the Journal of the Endocrine Society. “We explored the previous SARS outbreak caused by the very similar virus SARS-CoV-1 to advise endocrinologists involved in...