Stool microbes make a challenging diagnosis easier SCHEMATIC SHOWING HOW THE MICROBIOME SIGNATURE FROM STOOL SAMPLES CAN BE USED TO TEST FOR CIRRHOSIS. view more CREDIT: SALK INSTITUTE LA JOLLA–(July 1, 2020) Chronic liver disease represents a major global public health problem affecting an estimated 844 million people, according to the World Health Organization. It...
Charcoal a weapon to fight superoxide-induced disease, injury
Nanomaterials soak up radicals, could aid treatment of COVID-19 ARTIFICIAL ENZYMES MADE OF TREATED CHARCOAL, SEEN IN THIS ATOMIC FORCE MICROSCOPE IMAGE, COULD HAVE THE POWER TO CURTAIL DAMAGING LEVELS OF SUPEROXIDES. HOUSTON – (July 1, 2020) – Artificial enzymes made of treated charcoal could have the power to curtail damaging levels of superoxides, radical...
Smart structures: Structural cells of the body control immune function
by Austrian Academy of Sciences Schematic outline of the study, which used genomic assays (RNA-seq, ATAC-seq, ChIPmentation, flow cytometry) to investigate epigenetic and transcription regulation in structural cells (endothelium, epithelium and fibroblast) from twelve mouse organs. Credit: Thomas Krausgruber / CeMM In a Nature paper, CeMM researchers report on the epigenetic and transcriptional regulation in...
Researchers develop a new ultrafast insulin
by Taylor Kubota, Stanford University Researchers at Stanford University are developing a new insulin formulation that begins to take effect almost immediately upon injection, potentially working four times as fast as current commercial fast-acting insulin formulations. The researchers focused on so-called monomeric insulin, which has a molecular structure that, according to theory, should allow it...
Loss of intestinal goblet cells causes fatal disease after stem cell transplantation
by Hokkaido University In mice large intestine, the goblet cells (blue) are significantly reduced in number after allogeneic bone marrow transplantation (right), comparing to a control syngeneic recipients (left). Allogeneic stem cell transplantation can cause a loss of protective goblet cells from the colon’s inner lining, which can be fatal. But boosting those cells beforehand...
Experimental HIV drug seems effective at a twice-a-year dose, study finds
By NATALYA ORTOLANO @NatOrtolanoJULY 1, 2020 An experimental new HIV treatment could, with just one dose, reduce the amount of virus in an infected person for up to six months. But experts aren’t convinced the advance will significantly change how we treat HIV anytime soon. A group of researchers from Gilead Sciences developed a new...
Age research: A low level of the stress hormone cortisol contributes to the ageing process
SAARLAND UNIVERSITY WHY DO WE AGE? WHAT EXACTLY IS HAPPENING IN OUR BODIES? AND CAN WE DO ANYTHING ABOUT IT? MANKIND HAS SOUGHT ANSWERS TO THESE QUESTIONS SINCE TIME IMMEMORIAL. WHILE THE… view more CREDIT: IRIS MAURER Why do we age? What exactly is happening in our bodies? And can we do anything about it?...
The combination of four drugs at low doses is more effective in the treatment of a lu
IDIBELL-BELLVITGE BIOMEDICAL RESEARCH INSTITUTE BELLVITGE BIOMEDICAL RESEARCH INSTITUTE (IDIBELL) view more CREDIT: BELLVITGE BIOMEDICAL RESEARCH INSTITUTE (IDIBELL) Inhibit the specific activity of a protein affected by a mutation using high doses of a drug is the usual treatment for many cancers. Despite in the first instance this strategy is effective, leads to treatment resistance development...
Study shows asthma drug salbutamol’s potential as Alzheimer’s treatment
A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer’s disease LANCASTER UNIVERSITY A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia, affecting 47 million people worldwide and...
B-cell protectors
MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE IN THE HELMHOLTZ ASSOCIATION THE PROTEIN PDAP1 (RED) IS LOCATED IN THE CYTOPLASM OF B CELLS. view more CREDIT: DI VIRGILIO, MDC Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system’s most important...