by Maggie MacLellan, University of Western Ontario BrainsCAN researchers examined an area in the brain’s subcortical region called the basal forebrain that includes cholinergic neurons. These neurons are known to be severely damaged by Alzheimer’s disease. Credit: University of Western Ontario Researchers have moved one step closer to identifying targets for brain degeneration that occur...
by RCSI University of Medicine Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy. The study was led by researchers at FutureNeuro, the SFI Research Centre for Chronic and...
by Osaka University were defined as PD-1+ CD153+ cells in CD4+ T cells. The proportion of senescent T cells in visceral adipose tissues (VAT) of the high fat diet (HFD) control group was significantly increased compared with that in the VAT of the normal diet (ND) control group. CD153-CpG vaccination of HFD mice resulted in...
by Brita Belli, Yale University Researchers at Yale have identified a molecule that plays a key role in the body’s inflammatory response to overeating, which can lead to obesity, diabetes, and other metabolic diseases. The finding suggests that the molecule could be a promising therapeutic target to control this inflammation and keep metabolic diseases in...
IMAGE OF MOUSE ASTROCYTES SHOWING THE ACTIN CYTOSKELETON (RED) AND LYSOSOMES (GREEN) view more CREDIT: TANIA LOPEZ-HERNANDEZ Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system. This recycling process...
University of Alberta-led team develops synthetic molecule that stops production of toxic muscle-killing protein UNIVERSITY OF ALBERTA FACULTY OF MEDICINE & DENTISTRY UNIVERSITY OF ALBERTA MEDICAL GENETICIST TOSHIFUMA YOKOTA LED A RESEARCH TEAM THAT CREATED A POTENTIAL NEW TREATMENT FOR ONE OF THE MOST COMMON FORMS OF MUSCULAR DYSTROPHY. Researchers have designed a potential new...
by University of Leeds The blood flow in the surface blood vessels of a mouse that was not treated with M-3. Drugs that were developed to treat Alzheimer’s Disease could be re-purposed to prevent—or even reverse—the damage done to the blood vessels in people who are obese or suffer from type 2 diabetes, according to...
by Vanderbilt University Medical Center Deep Brain Stimulation (DBS) implanted in early stage Parkinson’s disease decreases the risk of disease progression and the need to prescribe multiple drugs to patients simultaneously, according to a five-year outcomes study of 30 patients released in the July 2020, issue of Neurology, the medical journal of the American Academy...
Not properly stored, it’s a source of antibiotic-resistant microbes UNIVERSITY OF CALIFORNIA – DAVIS Raw or unpasteurized cows’ milk from U.S. retail stores can hold a huge amount of antimicrobial-resistant genes if left at room temperature, according to a new study from researchers at the University of California, Davis. The study also found bacteria that...
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER EYEDROPS WITH A CASPASE-9 INHIBITOR PREVENT RETINAL INJURY FROM RETINAL VEIN OCCLUSION. IN THE LEFT IMAGE, RVO CAUSES SWELLING IN THE RETINA AND THE RETINAL LAYERS ARE LESS DISTINCT…. view more CREDIT: TROY LAB (CUIMC) NEW YORK, NY (June 29, 2020) — Researchers at Columbia University Irving Medical Center have...
