After a traumatic brain injury, why do some people regain skills quickly while others face long-lasting setbacks? Boston University neuroscientist Jerry Chen of BU’s Center for Systems Neuroscience and colleagues have been trying to answer this question by understanding which parts of the brain process sensory information and which remember different skills. The latest research...
Listeria protein provides a CRISPR ‘kill switch’
A single protein derived from a common strain of bacteria found in the soil will offer scientists a more precise way to edit RNA. The protein, called AcrVIA1, can halt the CRISPR-Cas13 editing process, according to new research from Cornell, Rockefeller University and the Memorial Sloan Kettering Cancer Center published in the journal Science. “We’re...
City of Hope: Mechanism that may lead to metabolic memory/sustained diabetes complications
New data show how early episodes of hyperglycemia can have long-term effects CITY OF HOPE CITY OF HOPE’S RAMA NATARAJAN, PH.D., THE NATIONAL BUSINESS PRODUCTS INDUSTRY PROFESSOR IN DIABETES RESEARCH, view more CREDIT: CITY OF HOPE DUARTE, Calif. — For people with diabetes, vascular complications like kidney disease and atherosclerosis, which can lead to poor...
Researchers identify possible drug target for prostate cancer
by Boston University School of Medicine Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases. Castration-resistant prostate cancer is a highly aggressive form of prostate cancer that often leads to the development of lethal metastases that kills more...
Skin stem cells shuffle sugars as they age
by University of Tsukuba Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at the molecular level. Now, researchers at the University of Tsukuba and...
Interaction dynamics between designer microrobots and the immune system
by Thamarasee Jeewandara , Medical Xpress Optimization of microswimmer shape for targeted drug delivery. Illustration of a future use case for the medical microrobots emphasizing an important design tradeoff. Double-helical magnetic microswimmers with filled internal cores are 3D-printed as concentrated drug-carrying bodies. Three morphological derivatives of the same design are tested with the same body...
Surrogate coronavirus may help researchers discover therapies and vaccines
by Albert Einstein College of Medicine To study the potentially lethal coronavirus, Albert Einstein College of Medicine scientists have turned a relatively harmless virus into a coronavirus “surrogate” that is much safer to work with. The research was described this month in Cell Host & Microbe. “Research on the ‘real’ coronavirus is limited by the...
Could THIS be the secret to living past 100? Scientists discover ‘master circuit’ that controls how cells age – and say reprogramming it could ‘dramatically’ lengthen lifespan
By NATALIE RAHHAL ACTING US HEALTH EDITOR University of California, San Diego, researchers found a cellular ‘master circuit’ that determines which of two ways yeast cells age in yeast By tweaking how proteins involved in the circuit interact, the scientists were able to create an entirely new pathway of aging for yeast cells Cells lived...
Latinx people more vulnerable to COVID-19, US study finds
An analysis of COVID-19 testing in the Baltimore-Washington metropolitan area of the United States found that Latinx people were around three times as likely to test positive, compared with any other ethnic or racial group. All data and statistics are based on publicly available data at the time of publication. Some information may be out...
Study helps to settle debate on roles of REM and non-REM sleep in visual learning
by Kerry Benson, Brown University This is a screenshot of a polysomnographic record (30 seconds) representing Rapid Eye Movement Sleep. EEG highlighted by red box. Eye movements highlighted by red line. Credit: MrSandman/ Wikipedia Which sleep stage is most important for learning: REM or non-REM? Does sleep improve learning by enhancing skills while people snooze,...