by German Cancer Research Center The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This was discovered by scientists at the German Cancer Research Center (DKFZ) and the Berlin Institute of Health (BIH). The enzyme that activates the dioxin receptor is produced in large quantities by tumor cells....
Failed Alzheimer’s drugs given new life after human gene discovery
By Rich Haridy August 19, 2020 A new study is questioning whether potential Alzheimer’s treatments previously found to be ineffective in human trials should be re-examined, after the discovery of a specific gene that can inhibit a therapy’s efficacy is only present in 75 percent of people. The long-standing cholinergic hypothesis for Alzheimer’s disease suggests...
Potential link for Alzheimer’s disease and common brain disease that mimics its symptoms
Conducting genetic screening in hundreds of autopsied brain samples, investigators identified shared molecular mechanisms in Alzheimer’s disease and LATE, a common brain disorder BRIGHAM AND WOMEN’S HOSPITAL Alzheimer’s disease is one of the most common causes of dementia, and while most people might know someone who is affected by it, the genetic factors behind the...
The behaviour of therapeutic antibodies in immunotherapy
Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells. However, in the more than 20 years since their use began, the molecular mechanisms that underlie this therapy are still little understood. For the first time, scientists from the...
Parental choices on junk food, healthy eating influence children
It’s no surprise that young children like sugar and salt in their food and develop their preferences based on what their parents feed them, but new research suggests that how parents view their own self-regulation also is a contributing factor. Food systems heavy in calories and light on recommended nutrition are a major factor contributing...
Researchers show children are silent spreaders of SARS-CoV-2
by Massachusetts General Hospital In the most comprehensive study of COVID-19 pediatric patients to date, Massachusetts General Hospital (MGH) and Mass General Hospital for Children (MGHfC) researchers provide critical data showing that children play a larger role in the community spread of COVID-19 than previously thought. In a study of 192 children ages 0-22, 49...
Oxford metastudy finds honey most effective treatment for coughs and colds
By Rich Haridy August 18, 2020 A new systematic review and meta-analysis from a trio of University of Oxford researchers is affirming the effectiveness of honey as a first-line treatment for upper respiratory tract infections (URTI). The study suggests antibiotics are ineffective for these kinds of minor coughs and colds, and honey offers superior symptomatic...
Hallucinations: What explains these tricks of the mind?
Hallucinations are sensory perceptions that appear in the absence of stimuli. Although they are often associated with illnesses such as schizophrenia, these phenomena can occur in the absence of mental ill health. But what explains these uncanny occurrences? Not all hallucinations occur due to psychotic disorders or psychedelic drugs. There are many types of hallucinations....
What does it mean when there is blood in stool?
It may be alarming to find blood in the toilet or after wiping. There are many possible causes, and some are relatively harmless, some require treatment, and some may warrant emergency care. Below, learn more about the possible causes of bloody stool, including those more common in children. Also, find out how doctors diagnose and...
Using a public restroom? Mask up!
Flushing public restroom toilets or urinals can spew clouds of particles carrying viruses, including COVID-19 AMERICAN INSTITUTE OF PHYSICS WASHINGTON, August 18, 2020 — Think you don’t need to worry about COVID-19 while using a public restroom? A group of researchers from Yangzhou University in China recently reported that flushing public restroom toilets can release...