The United States Food and Drug Administration recently approved Oliceridine, also known as “Olinvyk,” an opioid primarily concerned in treating severe acute pain, by biopharmaceutical company, Trevena, last August 7, 2020. After years of getting the FDA to approve the drug, Trevena, Inc., finally received approval this year. Trevena initially submitted the drug for review...
Why do some people stay sharp into their 90s, even if they have the amyloid plaques in the brain that are associated with Alzheimer’s disease? And why do others reach their 90s without ever developing any plaques? These questions are explored in a new study published in the July 22, 2020, online issue of Neurology®,...
by Natalie C. Tronson, The Conversation Of all frightening ways that the SARS-COV-2 virus affects the body, one of the more insidious is the effect of COVID-19 on the brain. It is now clear that many patients suffering from COVID-19 exhibit neurological symptoms, from loss of smell, to delirium, to an increased risk of stroke....
by Kate Wighton, Imperial College London Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 A new study has found one in ten people with inflammatory bowel disease visited their doctor with symptoms five years before receiving a diagnosis. Inflammatory bowel disease is a...
FUDAN UNIVERSITY SCIENTISTS FROM FUDAN UNIVERSITY DEVELOPED NOVEL STRATEGIES ACHIEVING ALLOGENEIC MICROGLIA REPLACEMENT IN THE CENTRAL NERVOUS SYSTEM. view more CREDIT: IMAGE CREDIT: XU ET AL, 2020, CELL REPORTS Researchers at Fudan University in Shanghai, China have developed three different techniques that successfully replace almost all malfunctioning microglia – each technique with its own advantage...
Rapid, inexpensive and non-invasive technique can track malignant melanoma progression or treatment response DE GRUYTER What if you could simply provide a urine sample rather than undergo a painful surgical procedure to find out if your cancer was responding to treatment? It may seem too good to be true, but researchers at Pavol Jozef Šafárik...
Tested in mice with genetically induced arthritis, the substance decreased the area affected, reduced local swelling, and assuaged the pain associated with the inflammatory process. ARTHRITIC MOUSE PAW TREATED WITH TPPU (LEFT) AND UNTREATED PAW OF ANOTHER ARTHRITIC MOUSE. By José Tadeu Arantes | Agência FAPESP – Arthritis affects almost 2% of the world’s population,...
Electrostatic interactions enhance the spike protein’s bond to host cells NORTHWESTERN UNIVERSITY A COMPUTER MODEL SHOWING THE POLYBASIC CLEAVAGE SITES, LOCATED ON THE NOVEL CORONAVIRUS’ PROTEIN SPIKE. view more CREDIT: NORTHWESTERN UNIVERSITY EVANSTON, Ill. — Northwestern University researchers have uncovered a new vulnerability in the novel coronavirus’ infamous spike protein — illuminating a relatively simple,...
Silky material uses magnetic particles to regrow bone By Ben Coxworth August 10, 2020 It was just a couple of months ago that we heard about an implantable material that electrically stimulates bone cells, causing them to reproduce. Now, scientists have created a similar substance that utilizes magnetism. There are already a number of experimental...
by RMIT University The study, conducted by an international team and led by RMIT University’s Professor Christian Doerig, outlines a strategy that could save years of drug discovery research and millions of dollars in drug development by repurposing existing treatments designed for other diseases such as cancer. The approach shows so much promise it has...
