Month: <span>August 2020</span>

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Promising new treatment of advanced skin cancer
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Promising new treatment of advanced skin cancer

A new type of immunotherapy for the skin cancer malignant melanoma shows promising results. Three severely ill patients are now long-term survivors. The study, published in OncoImmunology, is the result of a collaboration between researchers at Karolinska Institutet and Karolinska University Hospital. “Immunotherapy is based on activation of the body’s own immune defense to eliminate...

Nanocatalysts that remotely control chemical reactions inside living cells
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Nanocatalysts that remotely control chemical reactions inside living cells

POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) DIAGRAM OF REMOTELY CONTROLLED CATALYSIS IN LIVING CELLS USING MAG-NER AND THE ELECTRON MICROSCOPE IMAGE OF MAG-NERview more CREDIT: IN SU LEE (POSTECH) The enzymes responsible for catalytic reactions in our body’s biological reactions are difficult to use for diagnosis or treatment as they react only to certain...

The CNIO pave the way for a future gene therapy to reverse pulmonary fibrosis associated with ageing
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The CNIO pave the way for a future gene therapy to reverse pulmonary fibrosis associated with ageing

CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) DEVELOPMENT OF THE INITIAL STAGES OF PULMONARY FIBROSIS ASSOCIATED WITH AGEING IN NON-TREATED MICE (LEFT), THAT CAN BE PREVENTED IN MICE TREATED WITH THE TELOMERASE GENE THERAPY (RIGHT). view more CREDIT: CNIO Idiopathic pulmonary fibrosis is a potentially lethal disease for which there is currently no cure and that...

Researchers find new potential treatment for prion diseases
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Researchers find new potential treatment for prion diseases

by Oxford University Press A new study in Nucleic Acids Research, published by Oxford University Press, suggests a possible effective treatment strategy for patients suffering from prion disease. Prion disease is a rapidly fatal and currently untreatable neurodegenerative disease. While prion disease is quite rare, it typically causes rapid neurodegeneration. About 300 cases of prion...

New treatment targets found for blinding retinal disease
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New treatment targets found for blinding retinal disease

by Medical College of Georgia at Augusta University When the eye isn’t getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to...

New approach to treating osteoarthritis advances
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New approach to treating osteoarthritis advances

by NYU Langone Health The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body’s millions of cells. The molecule most used to store that energy is called adenosine triphosphate, or ATP. Along with this central role...

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COVID-19 may have a longer incubation period, suggests probability analysis of Wuhan cases

Estimation of incubation period distribution of COVID-19 using disease onset forward time: A novel cross-sectional and forward follow-up study AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE By applying the renewal theory in probability to reduce recall bias in initial case reports, scientists have come up with a new estimate for the incubation period of COVID-19....

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Reducing urinary protein for patients with rare kidney disease slows kidney decline

Even without full remission, reducing proteinuria in patients with FSGS allows their kidneys to function longer and extends time to end stage kidney disease CHILDREN’S NATIONAL HOSPITAL Reducing the amount of protein in the urine of patients with focal segmental glomerulosclerosis (FSGS), a rare disease in which scar tissue forms on the parts of the...

Exercise Enhancement
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Exercise Enhancement

Loss of a specific enzyme increases fat metabolism and exercise endurance in mice. Sugars and fats are the primary fuels that power every cell, tissue, and organ. For most cells, sugar is the energy source of choice, but when nutrients are scarce, such as during starvation or extreme exertion, cells will switch to breaking down...

The behavior of therapeutic antibodies in immunotherapy
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The behavior of therapeutic antibodies in immunotherapy

by CNRS Human antigen CD20 molecules (blue and pink) expressed on the surface of B cells are recognised by type 1 (green), and type 2 (orange) therapeutic antibodies. Only type 1 antibodies can potently recruit complement C1 component (light brown) to elicit complement pathway. Credit: Nicolas Reyes Since the late 1990s, immunotherapy has been the...