Month: <span>August 2020</span>

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New method to help spot gastric cancer cells
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New method to help spot gastric cancer cells

by Chinese Academy of Sciences Gastric cancer is the third leading cause of cancer death worldwide, accounting for over 1,000,000 new cases and nearly 800,000 deaths per year. The poor prognosis of gastric cancer is largely due to the difficulty in early diagnosis of peritoneal metastasis. Separation and characterization of cancer cells are essential for...

Drug prevents multiple sclerosis relapses in phase 3 trial
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Drug prevents multiple sclerosis relapses in phase 3 trial

by University of California, San Francisco A newly completed phase 3, multicenter clinical trial has found that an immune-modulating drug can silence inflammatory disease activity in a large majority of patients with relapsing multiple sclerosis (RMS)—the most common form of the illness, in which symptoms wax and wane. MS is an autoimmune disease in which...

New light shed on cell migration
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New light shed on cell migration

This news or article is intended for readers with certain scientific or professional knowledge in the field. Researchers at the IRCM, IRIC and University of Cambridge work together to reveal a mechanism involved in the formation of metastases. The 3D structure of the ELMO / DOCK2 complex, an important molecular machine that plays a crucial role in...

Fitness in Humans Acts to Reduce Inflammation, But Does Not Reduce the Burden of Cellular Senescence in Muscle Tissue
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Fitness in Humans Acts to Reduce Inflammation, But Does Not Reduce the Burden of Cellular Senescence in Muscle Tissue

This news or article is intended for readers with certain scientific or professional knowledge in the field. Fitness produced by training is here shown to correlate with reduced inflammatory signaling, but has no effect on the burden of senescent cells in old muscle tissue. This is interesting, as the accumulation of senescent cells with age...

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Autism: How a gene alteration modifies social behavior

Researchers report on a treatment approach that could normalize social behavior in autism UNIVERSITY OF BASEL A team of researchers at the Biozentrum, University of Basel, has discovered a new connection between a genetic alteration and social difficulties related to autism: A mutation in the neuroligin-3 gene reduces the effect of the hormone oxytocin. In...

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Antibiotics linked to higher heart disease risk in individuals with type 1 diabetes

Results from a study published in the Journal of Internal Medicine suggest that bacterial infections may elevate the risk of coronary heart disease in individuals with type 1 diabetes. Among 3,781 individuals with type 1 diabetes, 370 developed coronary heart disease over an average follow-up of 13.7 years. Antibiotic purchases, reflecting bacterial infections in outpatient...

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The yin and yang of inflammation controlled by a single molecule

Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a protein called histone deacetylase 3 (HDAC3) as the orchestrator of the immune system’s inflammation response to infection. By using both specially cultured cells and small animal models, HDAC3 was found to be directly involved in the production of agents...

Consumption of a blueberry enriched diet by women for six weeks alters determinants of human muscle progenitor cell function
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Consumption of a blueberry enriched diet by women for six weeks alters determinants of human muscle progenitor cell function

A NEW STUDY INVESTIGATED HOW SERUM FROM SUBJECTS CONSUMING A DIET ENRICHED WITH BLUEBERRIES WOULD AFFECT THE CELLS RESPONSIBLE FOR MUSCLE GROWTH AND REPAIR.view more CREDIT: U.S. HIGHBUSH BLUEBERRY COUNCIL FOLSOM, Calif. – August 5, 2020 – A new research study, published in the Journal of Nutrition, investigated how serum from subjects consuming a diet...

Scientists discover novel drug target for pancreatic cancer
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Scientists discover novel drug target for pancreatic cancer

SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE ANINDYA BAGCHI, PH.D., ASSOCIATE PROFESSOR IN THE TUMOR INITIATION AND MAINTENANCE PROGRAM AT SANFORD BURNHAM PREBYS. view more CREDIT: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that stops the deadly spread of...

Osteopontin, a protein not always as bad as it is made out to be
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Osteopontin, a protein not always as bad as it is made out to be

The UPV/EHU-University of the Basque Country shows that maintaining osteopontin delays the onset of metabolic fatty liver disease during ageing UNIVERSITY OF THE BASQUE COUNTRY THE STUDY INDICATES THAT OSTEOPONTIN IS NECESSARY TO PREVENT THE EARLY ONSET OF NON-ALCOHOLIC FATTY LIVER DISEASE LINKED TO AGEING view more Metabolic fatty liver disease, known as non-alcoholic fatty...