Month: <span>August 2020</span>

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Newly discovered mutation could point to heart disease therapeutic target
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Newly discovered mutation could point to heart disease therapeutic target

by Carnegie Institution for Science lipid from the yolk of a zebrafish through the circulation to the growing tissues of the embryo. Later in development, they will also carry lipids from the intestine and liver. While normal, wild-type, zebrafish have clear yolks (top image), zebrafish with mutations in Mtp have abnormally opaque yolks because they...

Intranasal vaccine platform has potential for more effective vaccines, fewer side effects
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Intranasal vaccine platform has potential for more effective vaccines, fewer side effects

by University of Chicago Medical Center The ongoing COVID-19 pandemic is shining a bright spotlight on vaccine development. As numerous vaccines race through clinical trials, physicians and researchers continue to work on developing new vaccine technologies to generate the most effective vaccines with the fewest side effects. A new proof-of-concept study by researchers at the...

Intestinal Insight
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Intestinal Insight

Every year, about 250,000 people in the U.S. with severe obesity and related health conditions undergo bariatric surgeries. These procedures can help people lose excess weight and rapidly improve high blood sugar, high blood pressure and heart disease. Some of these changes result from restricting the amount of food the stomach can hold. Others arise...

Epirubicin-loaded nanomedicines beat immune checkpoint blockade resistance in glioblastoma
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Epirubicin-loaded nanomedicines beat immune checkpoint blockade resistance in glioblastoma

INNOVATION CENTER OF NANOMEDICINE LEFT: HYDROPHOBIC EPIRUBISIN IS CONJUGATED TO ONE END OF HYDROPHILIC POLYETHYLENE GLYCOL (PEG) CHAIN WITH ASPARTATE-HYDRAZIDE AS A LINKER. IN WATER, THIS MOLECULE IS SELF-ASSEMBLED TO FORM NANO-MICELLES (EPI/M). UPPER… view more CREDIT: 2020 INNOVATION CENTER OF NANOMEDICINE Summary: A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the...

NSD2 enzyme appears to prevent cellular senescence
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NSD2 enzyme appears to prevent cellular senescence

Toward an era where aging can be controlled KUMAMOTO UNIVERSITY THE HUMAN BODY AND THE CELLS THAT MAKE IT UP HAVE A “PROGRAM ” FOR AGING. IT IS THOUGHT THAT THERE IS AN ACCUMULATION OF SENESCENT CELLS IN TISSUES AND ORGANS… view more CREDIT: PROFESSOR MITSUYOSHI NAKAO Researchers from Kumamoto University in Japan have used...

Brain noise contains unique signature of dream sleep
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Brain noise contains unique signature of dream sleep

by University of California – Berkeley When we dream, our brains are filled with noisy electrical activity that looks nearly identical to that of the awake brain. But University of California, Berkeley, researchers have pulled a signal out of the noise that uniquely defines dreaming, or REM sleep, potentially making it easier to monitor people...

Transgender and gender-diverse individuals more likely to be autistic: study
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Transgender and gender-diverse individuals more likely to be autistic: study

by University of Cambridge Transgender and gender-diverse adults are three to six times more likely as cisgender adults (individuals whose gender identity corresponds to their sex assigned at birth) to be diagnosed as autistic, according to a new study by scientists at the University of Cambridge’s Autism Research Centre. This research, conducted using data from...

Neuronal cultures advance ‘brain-on-a-chip’ technology
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Neuronal cultures advance ‘brain-on-a-chip’ technology

by Jeremy Thomas, Lawrence Livermore National Laboratory Laboratory team cultured rodent-derived neurons on microelectrode arrays and allowed the cultures to form networks, supplementing them with astrocytes and oligodendrocytes — cell types that play a critical role in neuronal health and function. Pictured is an immunofluorescence image of a complex culture, showing neurons (stained red), astrocytes...