Month: <span>September 2020</span>

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Biomarker predicts who will have severe COVID-19
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Biomarker predicts who will have severe COVID-19

by  The Korea Advanced Institute of Science and Technology (KAIST) Figure. Low glucocorticoid receptor (GR) expression led to excessive inflammation and lung damage by neutrophils through enhancing the expression of CXCL8 and other cytokines. Credit: The Korea Advanced Institute of Science and Technology (KAIST) KAIST researchers have identified key markers that could help pinpoint patients who...

Antibiotic pre-treatment reduces joint inflammation
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Antibiotic pre-treatment reduces joint inflammation

by Anne M Stark,  Lawrence Livermore National Laboratory Results indicate that treatment with the antibiotics prior to a severe articular injury slows down the development of post-traumatic osteoarthritis (PTOA) by enhancing the healing capabilities of the immune response. Credit: Lawrence Livermore National Laboratory Tearing an anterior cruciate ligament (ACL) can be an excruciatingly painful injury. Nearly...

New smart drug delivery system may help treatment for neurological disorders
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New smart drug delivery system may help treatment for neurological disorders

by Todd Bates,  Rutgers University This drug delivery system includes a porous biodegradable platform that can reduce nervous tissue inflammation and may help treat spinal cord injuries and other neurological disorders. A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and...

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The hormone glucagon may be a warning light for diabetes

UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Up to one in four Danes has an unhealthy accumulation of fat in the liver, also known as fatty liver. Fatty liver is rarely the cause of symptoms in itself, but people with fatty liver have an increased risk of developing diabetes. Exactly how the...

Why the dose matters: Study shows levels and anti-tumor effectiveness of a common drug vary widely
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Why the dose matters: Study shows levels and anti-tumor effectiveness of a common drug vary widely

UT SOUTHWESTERN MEDICAL CENTER IMAGE: ABOVE ARE IMAGES OF A TUMOR IN THE LUNG OF A PATIENT ON ITRACONAZOLE WHO TOOK PART IN THE STUDY, INCLUDING A MAP GENERATED FROM DYNAMIC CONTRAST-ENHANCED (DCE) MAGNETIC RESONANCE. DALLAS – Sept. 17, 2020 – When used to manage infections, the drug itraconazole is generally given at a single,...

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Coffee associated with improved survival in metastatic colorectal cancer patients

DANA-FARBER CANCER INSTITUTE BOSTON – In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute and other organizations report in a new study. The findings, based on data...

UC study sheds light on cancer treatment, COVID-19
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UC study sheds light on cancer treatment, COVID-19

UNIVERSITY OF CINCINNATI IMAGE: TRISHA WISE-DRAPER, MD, PHD, ASSOCIATE PROFESSOR OF MEDICINE IN THE DIVISION OF HEMATOLOGY ONCOLOGY AT THE UC COLLEGE OF MEDICINE AND LEAD AUTHOR. University of Cincinnati researchers have found that certain treatments for cancer may increase the chance of death if they contract COVID-19. These findings from a multicenter study, presented...

Scientists are working on vaccines that spread like a disease. What could possibly go wrong?
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Scientists are working on vaccines that spread like a disease. What could possibly go wrong?

By Filippa Lentzos, Guy Reeves, September 18, 2020 A worker conducts testing during the 2014 Ebola outbreak in Liberia. Once a COVID-19 vaccine is approved for public use, officials around the world will face the monumental challenge of vaccinating billions of people, a logistical operation rife with thorny ethical questions. What if instead of orchestrating complicated and resource-intensive campaigns...

CNIC researchers discover a mechanism allowing immune cells to regulate obesity
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CNIC researchers discover a mechanism allowing immune cells to regulate obesity

CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) IMAGE: FROM LEFT TO RIGHT: REBECA ACÍN-PÉREZ, SALVADOR IBORRA, JOSÉ ANTONIO ENRÍQUEZ AND DAVID SANCHO. Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of...

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Three common medications lower risk and mortality for lung cancer

INTERNATIONAL ASSOCIATION FOR THE STUDY OF LUNG CANCER DENVER–Combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology (JTO). The JTO is the official journal of the International Association for the Study of Lung Cancer. All three medications are...