by Karen Zusi, Broad Institute of MIT and Harvard Cross-section of mouse tissue expressing GFP (green) in all ENS nuclei, and tdTomato (red) in all ENS cells (neurons and glia). The section is also stained with DAPI (blue) to mark all nuclei and an anti-TUBB3 antibody (white) to mark all neurons. Credit: Eugene Drokhlyansky, Chris...
Brain imaging expertise supports new discoveries on decision-making process
by Toby Leigh, University of Plymouth Research carried out by a University academic has shed new light on the fundamentals of how, and why, we make the decisions we do. In two separate studies, UKRI Future Leader Fellow and Lecturer in Psychology, Dr. Elsa Fouragnan has used her expertise in functional magnetic resonance imaging (fMRI)...
COVID-19 and mRNA Vaccines—First Large Test for a New Approach
n January 10, Chinese researchers posted the novel coronavirus’ RNA sequence on a preprint server. Immediately, scientists who study genetic vaccines turned their efforts to the emerging pathogen that causes coronavirus disease 2019 (COVID-19). They knew that rapid response genetic platforms could shave precious weeks to months off development, crucial during a pandemic.\ They were...
Weak electric currents could help combat superbugs
Scientists have shown that currents measured in millionths of an amp kill bacteria by disrupting their outer membranes. The finding may inspire new antimicrobial technologies that use electricity to slow the spread of antibiotic resistant infections. New research suggesting that electricity can kill bacteria may have long-term implications for combating ‘superbugs.’ Scientists have known since...
Study examines the side effects of Alzheimer’s disease dementia drugs
Reviewed by Emily Henderson, B.Sc.Sep 3 2020 In a first of its kind study, a University of Houston researcher is examining two common drugs used for dementia in patients with Alzheimer’s disease to determine the extent to which they don’t mix well together and cause a cascading event of side effects, prompting the need for...
AI algorithm detects signs of Alzheimer’s disease through language
By Nick Lavars September 02, 2020 AI algorithms that analyze the language used by Alzheimer’s sufferers could become a useful tool in diagnosing the disease in its early stages With no cure and no straightforward way of diagnosing the disease, scientists are exploring every avenue when it comes to detecting Alzheimer’s during its early stages....
Dartmouth-led team engineers new treatment for drug-resistant bacterial infections
THAYER SCHOOL OF ENGINEERING AT DARTMOUTH A MOLECULAR MODEL OF THE F12 BIOTHERAPY SHOWS THE FOLD OF ITS POLYPEPTIDE BACKBONE. RESIDUAL T CELL EPITOPES ARE MAPPED ONTO THE STRUCTURE AND COLORED FROM WHITE (NO EPITOPES). The Centers for Disease Control and Prevention (CDC) has prioritized finding effective treatment of Methicillin-resistant Staphylococcus aureus (MRSA), one of...
Editing the immune response could make gene therapy more effective
ASSOCIATE PROFESSOR OF PATHOLOGY, MEMBER OF THE PITTSBURGH LIVER RESEARCH CENTER AND THE MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE view more CREDIT: UNIVERSITY OF PITTSBURGH PITTSBURGH, Sept. 3, 2020 – Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors...
Novel insights of how prostate cancer causes secondary tumors
UMEA UNIVERSITY ILLUSTRATION OF HOW THE PROTEIN SMAD7 ENHANCES THE DEVELOPMENT OF TUMORS BY REGULATING THE GENE EXPRESSION OF HDAC6 AND C-JUN. view more CREDIT: KEMAL AVICAN An increased awareness on a molecular level of what mechanisms prostate cancer cells use to become mobile and start spreading may in the long run provide new opportunities...
Wearable, portable invention offers options for treating antibiotic-resistant infections
PURDUE UNIVERSITY PURDUE UNIVERSITY INNOVATORS CREATED A WEARABLE INVENTION THAT OFFERS OPTIONS FOR TREATING ANTIBIOTIC-RESISTANT INFECTIONS AND WOUNDS. view more CREDIT: PURDUE UNIVERSITY/RAHIM RAHIMI WEST LAFAYETTE, Ind. – The rapid increase of life-threatening antibiotic-resistant infections has resulted in challenging wound complications with limited choices of effective treatments. About 6 million people in the United States...